DataSet Record GDS2681: Expression Profiles Data Analysis Tools Sample Subsets
Title: Caloric restriction effect on aged cochlea
Cluster AnalysisGDS2681 Cluster Image
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Summary: Analysis of cochleas of 15 month old C57BL/6 (B6) animals on a calorie restricted diet. The B6 strain is a model of age-related hearing loss or presbycusis. Caloric restriction (CR) prevents late-onset presbycusis in B6. Results provide insight into the molecular basis of this effect of CR.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Someya S, Yamasoba T, Weindruch R, Prolla TA et al. Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis. Neurobiol Aging 2007 Oct;28(10):1613-22. PMID: 16890326
Reference Series: GSE4786 Sample count: 9
Value type: count Series published: 2007/05/01