Ecdysone receptor knockdown effect on larval metamorphosis
Summary:
Analysis of ecdysone receptor (EcR) depleted animals 4 hours before to 4 hours after the start of pupariation. EcR is part of receptor complex for 20-hydroxyecdysone (20E), a hormone that triggers developmental transitions in insects. Results provide insight into the mechanisms regulated by 20E.
Beckstead RB, Lam G, Thummel CS. The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis. Genome Biol 2005;6(12):R99. PMID: 16356271