Analysis of 2T3 osteoblasts following 3 days of simulated microgravity using the rotating wall vessel (RWV). Weightlessness or microgravity of spaceflight induces bone loss due in part to decreased bone formation. Results provide insight into the molecular mechanisms regulating bone formation.
Patel MJ, Liu W, Sykes MC, Ward NE et al. Identification of mechanosensitive genes in osteoblasts by comparative microarray studies using the rotating wall vessel and the random positioning machine. J Cell Biochem 2007 Jun 1;101(3):587-99. PMID: 17243119
