Analysis of CD11b+ splenocytes from tumor-bearing animals. Tumor development often leads to the accumulation of CD11b+ GR-1 myeloid cells. Results provide insight into the molecular basis of the immunosuppressive activity exhibited by tumor-induced CD11b+ splenocytes.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Gallina G, Dolcetti L, Serafini P, De Santo C et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 2006 Oct;116(10):2777-90. PMID: 17016559
