Analysis of mock and deltaNp73alpha-expressing C2C12 myoblasts 6 and 24 hours after shifting the cells to a differentiation medium. DeltaNp73alpha, a p73alpha isoform, functions as a transdominant inhibitor of other p53 family members, interfering with multiple developmental programs.
Cam H, Griesmann H, Beitzinger M, Hofmann L et al. p53 family members in myogenic differentiation and rhabdomyosarcoma development. Cancer Cell 2006 Oct;10(4):281-93. PMID: 17045206
