Runt-related transcription factor 2 null mutation effect on the embryonal bone (MG-U74C)
Summary:
Analysis of embryonic day 14.5 humeri of runt-related transcription factor 2 (Runx2) deficient animals. Runx2 is an essential factor for skeletogenesis and heterozygous loss causes cleidocranial dysplasia. Results provide insight into the molecular mechanisms underlying skeletogenesis.
GPL83:
[MG_U74Cv2] Affymetrix Murine Genome U74 Version 2 Array
Citation:
Hecht J, Seitz V, Urban M, Wagner F et al. Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Gene Expr Patterns 2007 Jan;7(1-2):102-12. PMID: 16829211
