Myc activation and deactivation effect on pancreatic islet beta cells
Summary:
Analysis of transgenic pancreatic islet beta cells after activation of Myc for up to 24 hours or activation for 21 days followed by deactivation for up to 6 days. Results provide insight into the molecular basis of Myc-driven tumorigenesis in vivo.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Lawlor ER, Soucek L, Brown-Swigart L, Shchors K et al. Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis. Cancer Res 2006 May 1;66(9):4591-601. PMID: 16651409
