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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1983 1
1984 1
1985 1
1987 2
1989 1
1991 2
1992 3
1993 4
1994 2
1995 7
1996 2
1997 4
1998 1
2000 3
2001 3
2002 3
2003 1
2004 2
2005 2
2006 1
2007 1
2008 2
2009 1
2010 2
2012 1
2014 2
2015 1
2016 1
2018 1
2019 2
2020 2
2021 1
2022 1
2023 4
2024 1

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67 results

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Page 1
Metformin and Systemic Metabolism.
He L. He L. Trends Pharmacol Sci. 2020 Nov;41(11):868-881. doi: 10.1016/j.tips.2020.09.001. Epub 2020 Sep 28. Trends Pharmacol Sci. 2020. PMID: 32994049 Free PMC article. Review.
Metformin can improve patients' hyperglycemia through significant suppression of hepatic glucose production. However, up to 300 times higher concentrations of metformin accumulate in the intestine than in the circulation, where it alters nutrient metabolism in intes …
Metformin can improve patients' hyperglycemia through significant suppression of hepatic glucose production. However, up to 300 times higher …
Umbilical cord pH, blood gases, and lactate at birth: normal values, interpretation, and clinical utility.
Olofsson P. Olofsson P. Am J Obstet Gynecol. 2023 May;228(5S):S1222-S1240. doi: 10.1016/j.ajog.2022.07.001. Epub 2023 Mar 19. Am J Obstet Gynecol. 2023. PMID: 37164495 Free article. Review.
In addition to an increase in H(+) concentration, the lactate production is accelerated during hypoxia and anaerobic metabolism. ...The ambition to increase neonatal hemoglobin and iron depots by delaying cord clamping after birth results in falsely ac …
In addition to an increase in H(+) concentration, the lactate production is accelerated during hypoxia and anaerobic me …
Malignant hyperthermia.
Gronert GA. Gronert GA. Anesthesiology. 1980 Nov;53(5):395-423. doi: 10.1097/00000542-198011000-00007. Anesthesiology. 1980. PMID: 6999950 Free article. Review.
In MH, skeletal muscle acutely and unexpectedly increases its oxygen consumption and lactate production, resulting in greater heat production, respiratory and metabolic acidosis, muscle ridigity, sympathetic stimulation, and increased cellular permeability. . …
In MH, skeletal muscle acutely and unexpectedly increases its oxygen consumption and lactate production, resulting in greater …
The Tumor Metabolic Microenvironment: Lessons from Lactate.
García-Cañaveras JC, Chen L, Rabinowitz JD. García-Cañaveras JC, et al. Cancer Res. 2019 Jul 1;79(13):3155-3162. doi: 10.1158/0008-5472.CAN-18-3726. Epub 2019 Jun 6. Cancer Res. 2019. PMID: 31171526 Free PMC article. Review.
Limited microenvironment concentration measurements suggest depletion of glucose and modest accumulation of lactate (less than 2-fold). Isotope tracer measurements show rapid lactate exchange between the tumor and circulation. Such exchange is catalyze …
Limited microenvironment concentration measurements suggest depletion of glucose and modest accumulation of lactate (less than …
Blood boosting and sport.
Ekblom BT. Ekblom BT. Baillieres Best Pract Res Clin Endocrinol Metab. 2000 Mar;14(1):89-98. doi: 10.1053/beem.2000.0056. Baillieres Best Pract Res Clin Endocrinol Metab. 2000. PMID: 10932813 Review.
Reinfusion of whole blood or packed red blood cells (RBCs) increasing the haemoglobin concentration ([Hb]) above the individual's normal values increases VO2max and enhances physical performance. During submaximal exercise heart rate and bloo
Reinfusion of whole blood or packed red blood cells (RBCs) increasing the haemoglobin concentration ([Hb]) above …
Clinical review: splanchnic ischaemia.
Jakob SM. Jakob SM. Crit Care. 2002 Aug;6(4):306-12. doi: 10.1186/cc1515. Epub 2002 Apr 8. Crit Care. 2002. PMID: 12225604 Free PMC article. Review.
Total liver blood flow is believed to be relatively protected when gut blood flow decreases, because hepatic arterial flow increases when portal venous flow decreases (the hepatic arterial buffer response [HABR]). However, there is evidence that the HABR is d …
Total liver blood flow is believed to be relatively protected when gut blood flow decreases, because hepatic arterial flow …
Control of glycaemia.
Gerich JE. Gerich JE. Baillieres Clin Endocrinol Metab. 1993 Jul;7(3):551-86. doi: 10.1016/s0950-351x(05)80207-1. Baillieres Clin Endocrinol Metab. 1993. PMID: 8379904 Review.
Maintenance of plasma glucose concentrations within a narrow range despite wide fluctuations in the demand (e.g. vigorous exercise) and supply (e.g. large carbohydrate meals) of glucose results from coordination of factors that regulate glucose release into and removal fro …
Maintenance of plasma glucose concentrations within a narrow range despite wide fluctuations in the demand (e.g. vigorous exercise) a …
Dichloroacetate.
Stacpoole PW, Greene YJ. Stacpoole PW, et al. Diabetes Care. 1992 Jun;15(6):785-91. doi: 10.2337/diacare.15.6.785. Diabetes Care. 1992. PMID: 1600837 Review.
A major site of action of the drug is pyruvate dehydrogenase (PDH), the rate-limiting enzyme of aerobic glucose oxidation. Stimulation of PDH by DCA increases peripheral oxidation of alanine and lactate, thereby interrupting the Cori and alanine cycles and reducing …
A major site of action of the drug is pyruvate dehydrogenase (PDH), the rate-limiting enzyme of aerobic glucose oxidation. Stimulation of PD …
Environmental bisphenol A exposure triggers trained immunity-related pathways in monocytes.
Dallio M, Ventriglia L, Romeo M, Scognamiglio F, Diano N, Moggio M, Cipullo M, Coppola A, Ziogas A, Netea MG, Federico A. Dallio M, et al. Front Immunol. 2023 Nov 23;14:1270391. doi: 10.3389/fimmu.2023.1270391. eCollection 2023. Front Immunol. 2023. PMID: 38077323 Free PMC article. Review.
In parallel, monocytes were isolated from whole blood and acutely stimulated or trained with BPA at three different concentrations (1 nM, 10 nM, 20 nM). ...Moreover, we proved the non-toxic effect of BPA at each experimental concentration by performing an MTT …
In parallel, monocytes were isolated from whole blood and acutely stimulated or trained with BPA at three different concentrations
Concepts of Lactate Metabolic Clearance Rate and Lactate Clamp for Metabolic Inquiry: A Mini-Review.
Emhoff CW, Messonnier LA. Emhoff CW, et al. Nutrients. 2023 Jul 20;15(14):3213. doi: 10.3390/nu15143213. Nutrients. 2023. PMID: 37513631 Free PMC article. Review.
Blood lactate concentration is sensitive to the metabolic state of tissues and organs as lactate rates of appearance and disposal/disappearance in the circulation rise and fall in response to physical exercise and other metabolic disturbances. .
Blood lactate concentration is sensitive to the metabolic state of tissues and organs as lactate rates of appear
67 results