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PubMed for id: 924181485

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Page 1
Flvcr1a deficiency promotes heme-based energy metabolism dysfunction in skeletal muscle.
Mistretta M, Fiorito V, Allocco AL, Ammirata G, Hsu MY, Digiovanni S, Belicchi M, Napoli L, Ripolone M, Trombetta E, Mauri P, Farini A, Meregalli M, Villa C, Porporato PE, Miniscalco B, Crich SG, Riganti C, Torrente Y, Tolosano E. Mistretta M, et al. Cell Rep. 2024 Mar 26;43(3):113854. doi: 10.1016/j.celrep.2024.113854. Epub 2024 Feb 26. Cell Rep. 2024. PMID: 38412099 Free article.
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis.
Petrillo S, De Giorgio F, Bertino F, Garello F, Bitonto V, Longo DL, Mercurio S, Ammirata G, Allocco AL, Fiorito V, Chiabrando D, Altruda F, Terreno E, Provero P, Munaron L, Genova T, Nóvoa A, Carlos AR, Cardoso S, Mallo M, Soares MP, Tolosano E. Petrillo S, et al. Angiogenesis. 2023 Aug;26(3):365-384. doi: 10.1007/s10456-023-09865-w. Epub 2023 Jan 11. Angiogenesis. 2023. PMID: 36631598 Free PMC article.
Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis.
Petrillo S, Chiabrando D, Genova T, Fiorito V, Ingoglia G, Vinchi F, Mussano F, Carossa S, Silengo L, Altruda F, Merlo GR, Munaron L, Tolosano E. Petrillo S, et al. Cell Death Differ. 2018 Mar;25(3):573-588. doi: 10.1038/s41418-017-0001-7. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229999 Free PMC article.
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation.
Chiabrando D, Marro S, Mercurio S, Giorgi C, Petrillo S, Vinchi F, Fiorito V, Fagoonee S, Camporeale A, Turco E, Merlo GR, Silengo L, Altruda F, Pinton P, Tolosano E. Chiabrando D, et al. J Clin Invest. 2012 Dec;122(12):4569-79. doi: 10.1172/JCI62422. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187127 Free PMC article.