PubMed (MeSH Keyword) for id: 73087

Year	Number of Results
1986	2
1987	1
1989	2
1993	1
1995	1
1996	3
1997	1
2000	1
2001	1
2002	1
2005	2
2007	1
2008	1
2009	4
2010	3
2011	15
2012	17
2013	15
2014	15
2015	19
2016	9
2017	10
2018	7
2019	14
2020	12
2021	10
2022	4
2023	3
2024	2

1

Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells.

Jacksi M, Schad E, Tantos A. Jacksi M, et al. Biomolecules. 2024 Apr 5;14(4):445. doi: 10.3390/biom14040445. Biomolecules. 2024. PMID: 38672463 Free PMC article.

2

Multi-Omics Integrated Analysis of the Protective Effect of EZH2 Inhibition in Mice with Renal Ischemia-Reperfusion Injury.

Zou S, Chen J, Zhou P, Xue M, Wu M, Wang L. Zou S, et al. Kidney Blood Press Res. 2024;49(1):196-207. doi: 10.1159/000537866. Epub 2024 Feb 18. Kidney Blood Press Res. 2024. PMID: 38368866 Free article.

3

Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia.

Yamazaki T, Mimura I, Kurata Y, Tanaka T, Nangaku M. Yamazaki T, et al. Physiol Rep. 2023 Sep;11(17):e15810. doi: 10.14814/phy2.15810. Physiol Rep. 2023. PMID: 37710084 Free PMC article.

4

3-deazaneplanocin A, a histone methyltransferase inhibitor, improved the chemoresistance induced under hypoxia in melanoma cells.

Hosokawa M, Tetsumoto S, Yasui M, Kono Y, Ogawara KI. Hosokawa M, et al. Biochem Biophys Res Commun. 2023 Oct 15;677:26-30. doi: 10.1016/j.bbrc.2023.08.003. Epub 2023 Aug 2. Biochem Biophys Res Commun. 2023. PMID: 37542772

5

Validation of EZH2 Inhibitor Efficiency in Anaplastic Thyroid Carcinoma Cell Lines.

Nakayama H, Saito N, Kasajima R, Suganuma N, Rino Y, Masudo K, Yamazaki H, Toda S, Sekihara K, Iwasaki H, Hoshino D. Nakayama H, et al. Anticancer Res. 2023 Mar;43(3):1073-1077. doi: 10.21873/anticanres.16252. Anticancer Res. 2023. PMID: 36854530

6

EZH2 inhibitor DZNep blocks cell proliferation of GCB-DLBCL cells by upregulating p16.

Wang P, Xu L, Fan Y, Li B, Chen P, Zhang X, Sun Y, Fu J. Wang P, et al. Leuk Lymphoma. 2022 Dec;63(14):3370-3377. doi: 10.1080/10428194.2022.2131411. Epub 2022 Oct 14. Leuk Lymphoma. 2022. PMID: 36239491

7

Low-Dose 5-Aza and DZnep Alleviate Acute Graft-Versus-Host Disease With Less Side Effects Through Altering T-Cell Differentiation.

Wang QY, Liu HH, Dong YJ, Liang ZY, Yin Y, Liu W, Wang QY, Wang Q, Sun YH, Xu WL, Han N, Li Y, Ren HY. Wang QY, et al. Front Immunol. 2022 Feb 24;13:780708. doi: 10.3389/fimmu.2022.780708. eCollection 2022. Front Immunol. 2022. PMID: 35281001 Free PMC article.

8

Vitamin C promotes anti-leukemia of DZNep in acute myeloid leukemia.

Long B, Shan Y, Sun Y, Wang T, Li X, Huang K, Zhang W, He Y, Wen R, Li Y, Mai Y, Feng Y, Zhang T, Kang B, Zhang C, Zhu Y, Gu J, Liu J, Zhang X, Pan G. Long B, et al. Biochim Biophys Acta Mol Basis Dis. 2022 May 1;1868(5):166357. doi: 10.1016/j.bbadis.2022.166357. Epub 2022 Feb 7. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35143932 Free article.

9

S-adenosylmethionine-dependent methyltransferase inhibitor DZNep blocks transcription and translation of SARS-CoV-2 genome with a low tendency to select for drug-resistant viral variants.

Kumar R, Khandelwal N, Chander Y, Nagori H, Verma A, Barua A, Godara B, Pal Y, Gulati BR, Tripathi BN, Barua S, Kumar N. Kumar R, et al. Antiviral Res. 2022 Jan;197:105232. doi: 10.1016/j.antiviral.2021.105232. Epub 2021 Dec 29. Antiviral Res. 2022. PMID: 34968527 Free PMC article.

10

DZNep promotes mouse bone defect healing via enhancing both osteogenesis and osteoclastogenesis.

Cao X, He W, Rong K, Xu S, Chen Z, Liang Y, Han S, Zhou Y, Yang X, Ma H, Qin A, Zhao J. Cao X, et al. Stem Cell Res Ther. 2021 Dec 20;12(1):605. doi: 10.1186/s13287-021-02670-6. Stem Cell Res Ther. 2021. PMID: 34930462 Free PMC article.

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