PubMed (GeneRIF) for id: 78943

Year	Number of Results
2002	1
2005	1
2007	1
2008	3
2009	3
2010	6
2011	9
2012	9
2013	8
2014	10
2015	12
2016	8
2017	10
2018	11
2019	8
2020	8
2021	13
2022	17
2023	5
2024	4

1

Specific Knockout of Notch-1 in Macrophages Modulate the Progression of Hepatic Insulin Resistance in HFD Fed Mice via Regulating IRE1α-XBP1 Signals.

Zhou W, Ren S, Lu Y, Wang Y, Feng L, Gao Q. Zhou W, et al. J Coll Physicians Surg Pak. 2024 May;34(5):527-532. doi: 10.29271/jcpsp.2024.05.527. J Coll Physicians Surg Pak. 2024. PMID: 38720211

2

Tumorous IRE1α facilitates CD8⁺T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma.

Yang Y, Wang S, Wang XX, Guo S, Wang H, Shi Q, Tian Y, Wang H, Zhao T, Zhang H, Zhang B, Gao T, Li C, Yi X, Guo W. Yang Y, et al. Cell Commun Signal. 2024 Jan 30;22(1):83. doi: 10.1186/s12964-024-01470-8. Cell Commun Signal. 2024. PMID: 38291473 Free PMC article.

3

BCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis.

Le Saux CJ, Ho TC, Brumwell AM, Kathiriya JJ, Wei Y, Hughes JB, Garakani K, Atabai K, Auyeung VC, Papa FR, Chapman HA. Le Saux CJ, et al. Am J Respir Cell Mol Biol. 2024 Apr;70(4):247-258. doi: 10.1165/rcmb.2023-0109OC. Am J Respir Cell Mol Biol. 2024. PMID: 38117250

4

Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown.

Reuschlé Q, Van Heddegem L, Bosteels V, Moncan M, Depauw S, Wadier N, Maréchal S, De Nolf C, Delgado V, Messai Y, Stolzenberg MC, Magérus A, Werck A, Olagne J, Li Q, Lefevre G, Korganow AS, Rieux-Laucat F, Janssens S, Soulas-Sprauel P. Reuschlé Q, et al. J Autoimmun. 2024 Jan;142:103152. doi: 10.1016/j.jaut.2023.103152. Epub 2023 Dec 9. J Autoimmun. 2024. PMID: 38071801

5

Impaired T cell IRE1α/XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction.

Smolgovsky S, Bayer AL, Kaur K, Sanders E, Aronovitz M, Filipp ME, Thorp EB, Schiattarella GG, Hill JA, Blanton RM, Cubillos-Ruiz JR, Alcaide P. Smolgovsky S, et al. J Clin Invest. 2023 Dec 15;133(24):e171874. doi: 10.1172/JCI171874. J Clin Invest. 2023. PMID: 37874641 Free PMC article.

6

Loss of DDRGK1 impairs IRE1α UFMylation in spondyloepiphyseal dysplasia.

Yang X, Zhou T, Wang X, Xia Y, Cao X, Cheng X, Cao Y, Ma P, Ma H, Qin A, Zhao J. Yang X, et al. Int J Biol Sci. 2023 Sep 4;19(15):4709-4725. doi: 10.7150/ijbs.82765. eCollection 2023. Int J Biol Sci. 2023. PMID: 37781516 Free PMC article.

7

Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration.

Massoudi D, Gorman S, Kuo YM, Iwawaki T, Oakes SA, Papa FR, Gould DB. Massoudi D, et al. Invest Ophthalmol Vis Sci. 2023 Apr 3;64(4):30. doi: 10.1167/iovs.64.4.30. Invest Ophthalmol Vis Sci. 2023. PMID: 37097227 Free PMC article.

8

Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging.

Cabral-Miranda F, Tamburini G, Martinez G, Ardiles AO, Medinas DB, Gerakis Y, Hung MD, Vidal R, Fuentealba M, Miedema T, Duran-Aniotz C, Diaz J, Ibaceta-Gonzalez C, Sabusap CM, Bermedo-Garcia F, Mujica P, Adamson S, Vitangcol K, Huerta H, Zhang X, Nakamura T, Sardi SP, Lipton SA, Kennedy BK, Henriquez JP, Cárdenas JC, Plate L, Palacios AG, Hetz C. Cabral-Miranda F, et al. EMBO J. 2022 Nov 17;41(22):e111952. doi: 10.15252/embj.2022111952. Epub 2022 Oct 31. EMBO J. 2022. PMID: 36314651 Free PMC article.

9

Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.

Shao R, Lou X, Xue J, Yang Y, Ning D, Chen G, Jiang L. Shao R, et al. Immunopharmacol Immunotoxicol. 2023 Jun;45(3):277-286. doi: 10.1080/08923973.2022.2138431. Epub 2022 Oct 27. Immunopharmacol Immunotoxicol. 2023. PMID: 36263912

10

The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus.

Chalmers FE, Mogre S, Rimal B, Son J, Patterson AD, Stairs DB, Glick AB. Chalmers FE, et al. Dev Biol. 2022 Dec;492:59-70. doi: 10.1016/j.ydbio.2022.09.009. Epub 2022 Sep 28. Dev Biol. 2022. PMID: 36179879 Free article.

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