PubMed (GeneRIF) for id: 5074

Year	Number of Results
1998	1
2001	1
2002	2
2003	4
2004	5
2005	5
2006	4
2007	3
2008	11
2009	7
2010	8
2011	6
2012	5
2013	7
2014	12
2015	4
2016	5
2017	7
2018	9
2019	4
2020	6
2021	2
2022	2
2024	0

1

CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis.

Zhang Y, Li Z, Wang J, Chen H, He R, Wu H. Zhang Y, et al. Cardiovasc Ther. 2022 Feb 15;2022:7125602. doi: 10.1155/2022/7125602. eCollection 2022. Cardiovasc Ther. 2022. PMID: 35251305 Free PMC article.

2

PAR4-Mediated PI3K/Akt and RhoA/ROCK Signaling Pathways Are Essential for Thrombin-Induced Morphological Changes in MEG-01 Cells.

Heo Y, Jeon H, Namkung W. Heo Y, et al. Int J Mol Sci. 2022 Jan 11;23(2):776. doi: 10.3390/ijms23020776. Int J Mol Sci. 2022. PMID: 35054966 Free PMC article.

3

Molecular mechanisms regulating Proteinase-Activated Receptors (PARs).

Chandrabalan A, Ramachandran R. Chandrabalan A, et al. FEBS J. 2021 Apr;288(8):2697-2726. doi: 10.1111/febs.15829. Epub 2021 Apr 6. FEBS J. 2021. PMID: 33742547 Free article. Review.

4

Determination of PAR4 numbers on the surface of human platelets: no effect of the single nucleotide polymorphism rs773902.

Li S, Tarlac V, Christanto RBI, French SL, Hamilton JR. Li S, et al. Platelets. 2021 Oct 3;32(7):988-991. doi: 10.1080/09537104.2020.1810654. Epub 2020 Aug 21. Platelets. 2021. PMID: 32819173

5

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling.

Rodriguez BAT, Bhan A, Beswick A, Elwood PC, Niiranen TJ, Salomaa V; FinnGen Study; Trégouët DA, Morange PE, Civelek M, Ben-Shlomo Y, Schlaeger T, Chen MH, Johnson AD. Rodriguez BAT, et al. Am J Hum Genet. 2020 Aug 6;107(2):211-221. doi: 10.1016/j.ajhg.2020.06.008. Epub 2020 Jul 9. Am J Hum Genet. 2020. PMID: 32649856 Free PMC article.

6

PAR4 activation involves extracellular loop 3 and transmembrane residue Thr153.

Han X, Hofmann L, de la Fuente M, Alexander N, Palczewski K; INVENT Consortium; Nieman MT. Han X, et al. Blood. 2020 Nov 5;136(19):2217-2228. doi: 10.1182/blood.2019004634. Blood. 2020. PMID: 32575122 Free PMC article.

7

Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Gα in live cells.

Kim Y, Ghil S. Kim Y, et al. Cell Commun Signal. 2020 Jun 9;18(1):86. doi: 10.1186/s12964-020-00552-7. Cell Commun Signal. 2020. PMID: 32517689 Free PMC article.

8

Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/ Smad4 axis driving the cells towards lethal EMT.

Mohd Faheem M, Rasool RU, Ahmad SM, Jamwal VL, Chakraborty S, Katoch A, Gandhi SG, Bhagat M, Goswami A. Mohd Faheem M, et al. Eur J Cell Biol. 2020 May;99(4):151076. doi: 10.1016/j.ejcb.2020.151076. Epub 2020 May 11. Eur J Cell Biol. 2020. PMID: 32439219

9

Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3.

Thayyullathil F, Cheratta AR, Pallichankandy S, Subburayan K, Tariq S, Rangnekar VM, Galadari S. Thayyullathil F, et al. Biochim Biophys Acta Mol Cell Res. 2020 Jul;1867(7):118692. doi: 10.1016/j.bbamcr.2020.118692. Epub 2020 Mar 2. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32135176 Free article.

10

Par-4 overexpression impedes leukemogenesis in the Eµ-TCL1 leukemia model through downregulation of NF-κB signaling.

Greene JT, Mani R, Ramaswamy R, Frissora F, Yano M, Zapolnik K, Harrington B, Wasmuth R, Tran M, Mo X, McKenna M, Rangnekar VM, Byrd JC, Bondada S, Muthusamy N. Greene JT, et al. Blood Adv. 2019 Apr 23;3(8):1255-1266. doi: 10.1182/bloodadvances.2018025973. Blood Adv. 2019. PMID: 30987970 Free PMC article.

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