PubMed (GeneRIF) for id: 231051

Year	Number of Results
2006	2
2007	1
2008	1
2009	1
2011	1
2013	1
2014	1
2015	1
2016	1
2017	4
2018	1
2019	2
2020	3
2021	1
2022	3
2023	4
2024	1

1

Macromolecular Complex Including MLL3, Carabin and Calcineurin Regulates Cardiac Remodeling.

Pane R, Laib L, Formoso K, Détrait M, Sainte-Marie Y, Bourgailh F, Ruffenach N, Faugeras H, Simon I, Lhuillier E, Lezoualc'h F, Conte C. Pane R, et al. Circ Res. 2024 Jan 5;134(1):100-113. doi: 10.1161/CIRCRESAHA.123.323458. Epub 2023 Dec 12. Circ Res. 2024. PMID: 38084599

2

MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.

Xie G, Lee JE, Senft AD, Park YK, Jang Y, Chakraborty S, Thompson JJ, McKernan K, Liu C, Macfarlan TS, Rocha PP, Peng W, Ge K. Xie G, et al. Nat Genet. 2023 Apr;55(4):693-705. doi: 10.1038/s41588-023-01356-4. Epub 2023 Apr 3. Nat Genet. 2023. PMID: 37012455

3

Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.

Simigdala N, Chalari A, Sklirou AD, Chavdoula E, Papafotiou G, Melissa P, Kafalidou A, Paschalidis N, Pateras IS, Athanasiadis E, Konstantopoulos D, Trougakos IP, Klinakis A. Simigdala N, et al. Cell Mol Life Sci. 2023 Mar 18;80(4):100. doi: 10.1007/s00018-023-04734-7. Cell Mol Life Sci. 2023. PMID: 36933062 Free PMC article.

4

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

Boileau RM, Chen KX, Blelloch R. Boileau RM, et al. Genome Biol. 2023 Mar 3;24(1):41. doi: 10.1186/s13059-023-02883-3. Genome Biol. 2023. PMID: 36869380 Free PMC article.

5

Circadian clock function does not require the histone methyltransferase MLL3.

Baxter M, Poolman T, Cunningham P, Hunter L, Voronkov M, Kitchen GB, Goosey L, Begley N, Kay D, Hespe A, Maidstone R, Loudon ASI, Ray DW. Baxter M, et al. FASEB J. 2022 Jul;36(7):e22356. doi: 10.1096/fj.202200368R. FASEB J. 2022. PMID: 35704036 Free PMC article.

6

KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming.

Na F, Pan X, Chen J, Chen X, Wang M, Chi P, You L, Zhang L, Zhong A, Zhao L, Dai S, Zhang M, Wang Y, Wang B, Zheng J, Wang Y, Xu J, Wang J, Wu B, Chen M, Liu H, Xue J, Huang M, Gong Y, Zhu J, Zhou L, Zhang Y, Yu M, Tian P, Fan M, Lu Z, Xue Z, Zhao Y, Yang H, Zhao C, Wang Y, Han J, Yang S, Xie D, Chen L, Zhong Q, Zeng M, Lowe SW, Lu Y, Liu Y, Wei Y, Chen C. Na F, et al. Nat Cancer. 2022 Jun;3(6):753-767. doi: 10.1038/s43018-022-00361-6. Epub 2022 Apr 21. Nat Cancer. 2022. PMID: 35449309 Free PMC article.

7

KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.

Limberger T, Schlederer M, Trachtová K, Garces de Los Fayos Alonso I, Yang J, Högler S, Sternberg C, Bystry V, Oppelt J, Tichý B, Schmeidl M, Kodajova P, Jäger A, Neubauer HA, Oberhuber M, Schmalzbauer BS, Pospisilova S, Dolznig H, Wadsak W, Culig Z, Turner SD, Egger G, Lagger S, Kenner L. Limberger T, et al. Mol Cancer. 2022 Mar 30;21(1):89. doi: 10.1186/s12943-022-01542-8. Mol Cancer. 2022. PMID: 35354467 Free PMC article.

8

Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy.

Chen R, Okeyo-Owuor T, Patel RM, Casey EB, Cluster AS, Yang W, Magee JA. Chen R, et al. Cell Rep. 2021 Feb 16;34(7):108751. doi: 10.1016/j.celrep.2021.108751. Cell Rep. 2021. PMID: 33596429 Free PMC article.

9

Long non-coding RNA DANCR regulate MLL3 and thereby it determines the progression of pancreatic cancer.

Liu Y, Li J, Yue B, Liang L, Zhang S, Chen Y. Liu Y, et al. J BUON. 2020 Jul-Aug;25(4):1954-1959. J BUON. 2020. PMID: 33099938 Free article.

10

MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.

Lee JE, Cho YW, Deng CX, Ge K. Lee JE, et al. Mol Cell Biol. 2020 Aug 14;40(17):e00209-20. doi: 10.1128/MCB.00209-20. Print 2020 Aug 14. Mol Cell Biol. 2020. PMID: 32601106 Free PMC article.

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