PubMed (GeneRIF) for id: 170752

Year	Number of Results
2010	1
2011	1
2013	2
2014	2
2015	2
2017	2
2018	1
2021	2
2024	0

1

Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4^-/-/Bco2^-/- double knockout mice.

Arunkumar R, Gorusupudi A, Li B, Blount JD, Nwagbo U, Kim HJ, Sparrow JR, Bernstein PS. Arunkumar R, et al. Exp Eye Res. 2021 Aug;209:108680. doi: 10.1016/j.exer.2021.108680. Epub 2021 Jun 20. Exp Eye Res. 2021. PMID: 34161819 Free PMC article.

2

β-carotene oxygenase 2 deficiency-triggered mitochondrial oxidative stress promotes low-grade inflammation and metabolic dysfunction.

Wu L, Lu P, Guo X, Song K, Lyu Y, Bothwell J, Wu J, Hawkins O, Clarke SL, Lucas EA, Smith BJ, Chowanadisai W, Hartson SD, Ritchey JW, Wang W, Medeiros DM, Li S, Lin D. Wu L, et al. Free Radic Biol Med. 2021 Feb 20;164:271-284. doi: 10.1016/j.freeradbiomed.2021.01.003. Epub 2021 Jan 13. Free Radic Biol Med. 2021. PMID: 33453359 Free PMC article.

3

Ablation of carotenoid cleavage enzymes (BCO1 and BCO2) induced hepatic steatosis by altering the farnesoid X receptor/miR-34a/sirtuin 1 pathway.

Lim JY, Liu C, Hu KQ, Smith DE, Wang XD. Lim JY, et al. Arch Biochem Biophys. 2018 Sep 15;654:1-9. doi: 10.1016/j.abb.2018.07.007. Epub 2018 Jul 11. Arch Biochem Biophys. 2018. PMID: 30006135

4

Ablation of β,β-carotene-9',10'-oxygenase 2 remodels the hypothalamic metabolome leading to metabolic disorders in mice.

Guo X, Wu L, Lyu Y, Chowanadisai W, Clarke SL, Lucas EA, Smith BJ, He H, Wang W, Medeiros DM, Lin D. Guo X, et al. J Nutr Biochem. 2017 Aug;46:74-82. doi: 10.1016/j.jnutbio.2017.02.019. Epub 2017 Apr 12. J Nutr Biochem. 2017. PMID: 28482236

5

Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice.

Wu L, Guo X, Hartson SD, Davis MA, He H, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, von Lintig J, Lin D. Wu L, et al. Mol Nutr Food Res. 2017 May;61(5):10.1002/mnfr.201600576. doi: 10.1002/mnfr.201600576. Epub 2017 Feb 9. Mol Nutr Food Res. 2017. PMID: 27991717 Free PMC article.

6

Characterization of the Role of β-Carotene 9,10-Dioxygenase in Macular Pigment Metabolism.

Babino D, Palczewski G, Widjaja-Adhi MA, Kiser PD, Golczak M, von Lintig J. Babino D, et al. J Biol Chem. 2015 Oct 9;290(41):24844-57. doi: 10.1074/jbc.M115.668822. Epub 2015 Aug 25. J Biol Chem. 2015. PMID: 26307071 Free PMC article.

7

Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice.

Ip BC, Liu C, Lichtenstein AH, von Lintig J, Wang XD. Ip BC, et al. J Nutr. 2015 Feb;145(2):268-76. doi: 10.3945/jn.114.200238. Epub 2014 Dec 10. J Nutr. 2015. PMID: 25644347 Free PMC article.

8

β-Carotene-9',10'-oxygenase status modulates the impact of dietary tomato and lycopene on hepatic nuclear receptor-, stress-, and metabolism-related gene expression in mice.

Tan HL, Moran NE, Cichon MJ, Riedl KM, Schwartz SJ, Erdman JW Jr, Pearl DK, Thomas-Ahner JM, Clinton SK. Tan HL, et al. J Nutr. 2014 Apr;144(4):431-9. doi: 10.3945/jn.113.186676. Epub 2014 Feb 19. J Nutr. 2014. PMID: 24553694 Free PMC article.

9

Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.

Amengual J, Widjaja-Adhi MAK, Rodriguez-Santiago S, Hessel S, Golczak M, Palczewski K, von Lintig J. Amengual J, et al. J Biol Chem. 2013 Nov 22;288(47):34081-34096. doi: 10.1074/jbc.M113.501049. Epub 2013 Oct 8. J Biol Chem. 2013. PMID: 24106281 Free PMC article.

10

Genetic ablation of carotene oxygenases and consumption of lycopene or tomato powder diets modulate carotenoid and lipid metabolism in mice.

Ford NA, Elsen AC, Erdman JW Jr. Ford NA, et al. Nutr Res. 2013 Sep;33(9):733-42. doi: 10.1016/j.nutres.2013.07.007. Epub 2013 Aug 13. Nutr Res. 2013. PMID: 24034573 Free PMC article.

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