PubMed (GeneRIF) for id: 12795

Year	Number of Results
2004	1
2007	1
2008	1
2009	1
2010	2
2011	1
2016	1
2021	1
2022	1
2023	1
2024	1

1

Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.

Fu J, Ling J, Li CF, Tsai CL, Yin W, Hou J, Chen P, Cao Y, Kang Y, Sun Y, Xia X, Jiang Z, Furukawa K, Lu Y, Wu M, Huang Q, Yao J, Hawke DH, Pan BF, Zhao J, Huang J, Wang H, Bahassi EIM, Stambrook PJ, Huang P, Fleming JB, Maitra A, Tainer JA, Hung MC, Lin C, Chiao PJ. Fu J, et al. Nat Commun. 2024 Apr 11;15(1):3149. doi: 10.1038/s41467-024-47242-3. Nat Commun. 2024. PMID: 38605037 Free PMC article.

2

TUBA1A licenses APC/C-mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3.

Wen J, Wang Q, Zhang W, Wang W. Wen J, et al. FEBS Lett. 2023 Dec;597(24):3072-3086. doi: 10.1002/1873-3468.14764. Epub 2023 Nov 7. FEBS Lett. 2023. PMID: 37873730

3

Inhibition of PLK3 Attenuates Tubular Epithelial Cell Apoptosis after Renal Ischemia-Reperfusion Injury by Blocking the ATM/P53-Mediated DNA Damage Response.

Deng W, Wei X, Xie Z, Zhang R, Dong Z, Zhang J, Luo Y, Cheng Q, Wang R, Li H, Na N. Deng W, et al. Oxid Med Cell Longev. 2022 Jun 24;2022:4201287. doi: 10.1155/2022/4201287. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35783188 Free PMC article.

4

The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3.

Vaughan CA, Singh S, Subler MA, Windle JJ, Inoue K, Fry EA, Pillappa R, Grossman SR, Windle B, Andrew Yeudall W, Deb SP, Deb S. Vaughan CA, et al. Nat Commun. 2021 Jan 29;12(1):704. doi: 10.1038/s41467-021-20928-8. Nat Commun. 2021. PMID: 33514736 Free PMC article.

5

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.

Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM. Goetz JJ, et al. PLoS One. 2016 Mar 7;11(3):e0150878. doi: 10.1371/journal.pone.0150878. eCollection 2016. PLoS One. 2016. PMID: 26949938 Free PMC article.

6

Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells.

Kostyak JC, Naik UP. Kostyak JC, et al. PLoS One. 2011 Jan 14;6(1):e14513. doi: 10.1371/journal.pone.0014513. PLoS One. 2011. PMID: 21264284 Free PMC article.

7

Regulation of PTEN stability and activity by Plk3.

Xu D, Yao Y, Jiang X, Lu L, Dai W. Xu D, et al. J Biol Chem. 2010 Dec 17;285(51):39935-42. doi: 10.1074/jbc.M110.166462. Epub 2010 Oct 12. J Biol Chem. 2010. PMID: 20940307 Free PMC article.

8

Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha.

Xu D, Yao Y, Lu L, Costa M, Dai W. Xu D, et al. J Biol Chem. 2010 Dec 10;285(50):38944-50. doi: 10.1074/jbc.M110.160325. Epub 2010 Oct 1. J Biol Chem. 2010. PMID: 20889502 Free PMC article.

9

Stimulation of polo-like kinase 3 mRNA decay by tristetraprolin.

Horner TJ, Lai WS, Stumpo DJ, Blackshear PJ. Horner TJ, et al. Mol Cell Biol. 2009 Apr;29(8):1999-2010. doi: 10.1128/MCB.00982-08. Epub 2009 Feb 2. Mol Cell Biol. 2009. PMID: 19188452 Free PMC article.

10

Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions.

Yang Y, Bai J, Shen R, Brown SA, Komissarova E, Huang Y, Jiang N, Alberts GF, Costa M, Lu L, Winkles JA, Dai W. Yang Y, et al. Cancer Res. 2008 Jun 1;68(11):4077-85. doi: 10.1158/0008-5472.CAN-07-6182. Cancer Res. 2008. PMID: 18519666 Free PMC article.

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