PubMed (GeneRIF) for id: 11262

Year	Number of Results
2002	1
2010	2
2015	1
2016	1
2018	2
2019	1
2022	3
2024	0

1

SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response.

Tanagala KKK, Morin-Baxter J, Carvajal R, Cheema M, Dubey S, Nakagawa H, Yoon A, Cheng YL, Taylor A, Nickerson J, Mintz A, Momen-Heravi F. Tanagala KKK, et al. J Immunother Cancer. 2022 Dec;10(12):e005088. doi: 10.1136/jitc-2022-005088. J Immunother Cancer. 2022. PMID: 36600652 Free PMC article.

2

Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease.

Fraschilla I, Amatullah H, Rahman RU, Jeffrey KL. Fraschilla I, et al. Cell Host Microbe. 2022 Oct 12;30(10):1370-1381.e5. doi: 10.1016/j.chom.2022.08.018. Epub 2022 Sep 20. Cell Host Microbe. 2022. PMID: 36130593 Free PMC article.

3

Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.

Amatullah H, Fraschilla I, Digumarthi S, Huang J, Adiliaghdam F, Bonilla G, Wong LP, Rivard ME, Beauchamp C, Mercier V, Goyette P, Sadreyev RI, Anthony RM, Rioux JD, Jeffrey KL. Amatullah H, et al. Cell. 2022 Aug 18;185(17):3232-3247.e18. doi: 10.1016/j.cell.2022.06.048. Epub 2022 Aug 10. Cell. 2022. PMID: 35952671 Free PMC article.

4

Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain.

Zucchelli C, Tamburri S, Filosa G, Ghitti M, Quilici G, Bachi A, Musco G. Zucchelli C, et al. Biochim Biophys Acta Gen Subj. 2019 Feb;1863(2):456-465. doi: 10.1016/j.bbagen.2018.11.011. Epub 2018 Nov 19. Biochim Biophys Acta Gen Subj. 2019. PMID: 30465816 Free article.

5

SP140 regulates the expression of immune-related genes associated with multiple sclerosis and other autoimmune diseases by NF-κB inhibition.

Karaky M, Fedetz M, Potenciano V, Andrés-León E, Codina AE, Barrionuevo C, Alcina A, Matesanz F. Karaky M, et al. Hum Mol Genet. 2018 Dec 1;27(23):4012-4023. doi: 10.1093/hmg/ddy284. Hum Mol Genet. 2018. PMID: 30102396

6

Whole Genome DNA Methylation Analysis of Obstructive Sleep Apnea: IL1R2, NPR2, AR, SP140 Methylation and Clinical Phenotype.

Chen YC, Chen TW, Su MC, Chen CJ, Chen KD, Liou CW, Tang P, Wang TY, Chang JC, Wang CC, Lin HC, Chin CH, Huang KT, Lin MC, Hsiao CC. Chen YC, et al. Sleep. 2016 Apr 1;39(4):743-55. doi: 10.5665/sleep.5620. Sleep. 2016. PMID: 26888452 Free PMC article.

7

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

Matesanz F, Potenciano V, Fedetz M, Ramos-Mozo P, Abad-Grau Mdel M, Karaky M, Barrionuevo C, Izquierdo G, Ruiz-Peña JL, García-Sánchez MI, Lucas M, Fernández Ó, Leyva L, Otaegui D, Muñoz-Culla M, Olascoaga J, Vandenbroeck K, Alloza I, Astobiza I, Antigüedad A, Villar LM, Álvarez-Cermeño JC, Malhotra S, Comabella M, Montalban X, Saiz A, Blanco Y, Arroyo R, Varadé J, Urcelay E, Alcina A. Matesanz F, et al. Hum Mol Genet. 2015 Oct 1;24(19):5619-27. doi: 10.1093/hmg/ddv256. Epub 2015 Jul 7. Hum Mol Genet. 2015. PMID: 26152201

8

Genetic susceptibility for chronic lymphocytic leukemia among Chinese in Hong Kong.

Lan Q, Au WY, Chanock S, Tse J, Wong KF, Shen M, Siu LP, Yuenger J, Yeager M, Hosgood HD 3rd, Purdue MP, Liang R, Rothman N. Lan Q, et al. Eur J Haematol. 2010 Dec;85(6):492-5. doi: 10.1111/j.1600-0609.2010.01518.x. Eur J Haematol. 2010. PMID: 20731705 Free PMC article.

9

Genetic susceptibility variants for chronic lymphocytic leukemia.

Slager SL, Goldin LR, Strom SS, Lanasa MC, Spector LG, Rassenti L, Leis JF, Camp NJ, Kay NE, Vachon CM, Glenn M, Weinberg JB, Rabe KG, Cunningham JM, Achenbach SJ, Hanson CA, Marti GE, Call TG, Caporaso NE, Cerhan JR. Slager SL, et al. Cancer Epidemiol Biomarkers Prev. 2010 Apr;19(4):1098-102. doi: 10.1158/1055-9965.EPI-09-1217. Epub 2010 Mar 23. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20332261 Free PMC article.

10

Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1.

Madani N, Millette R, Platt EJ, Marin M, Kozak SL, Bloch DB, Kabat D. Madani N, et al. J Virol. 2002 Nov;76(21):11133-8. doi: 10.1128/jvi.76.21.11133-11138.2002. J Virol. 2002. PMID: 12368356 Free PMC article.

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