PubMed (GeneRIF) for id: 10670

Year	Number of Results
2015	3
2016	1
2017	3
2018	1
2019	5
2020	4
2021	2
2023	2
2024	0

1

RAGA prevents tumor immune evasion of LUAD by promoting CD47 lysosome degradation.

Zhang L, Yu J, Zheng M, Zhen H, Xie Q, Zhang C, Zhou Z, Jin G. Zhang L, et al. Commun Biol. 2023 Feb 23;6(1):211. doi: 10.1038/s42003-023-04581-z. Commun Biol. 2023. PMID: 36823443 Free PMC article.

2

Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.

Cui Z, Napolitano G, de Araujo MEG, Esposito A, Monfregola J, Huber LA, Ballabio A, Hurley JH. Cui Z, et al. Nature. 2023 Feb;614(7948):572-579. doi: 10.1038/s41586-022-05652-7. Epub 2023 Jan 25. Nature. 2023. PMID: 36697823 Free PMC article.

3

An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.

Egri SB, Shen K. Egri SB, et al. J Biol Chem. 2021 Jul;297(1):100861. doi: 10.1016/j.jbc.2021.100861. Epub 2021 Jun 9. J Biol Chem. 2021. PMID: 34116056 Free PMC article.

4

Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation.

Kim SH, Choi JH, Wang P, Go CD, Hesketh GG, Gingras AC, Jafarnejad SM, Sonenberg N. Kim SH, et al. Mol Cell. 2021 Jan 21;81(2):398-407.e4. doi: 10.1016/j.molcel.2020.11.036. Epub 2020 Dec 18. Mol Cell. 2021. PMID: 33340489 Free article.

5

The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction.

Yang S, Zhang Y, Ting CY, Bettedi L, Kim K, Ghaniam E, Lilly MA. Yang S, et al. Dev Cell. 2020 Nov 9;55(3):272-288.e5. doi: 10.1016/j.devcel.2020.08.006. Epub 2020 Sep 7. Dev Cell. 2020. PMID: 32898476 Free PMC article.

6

Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.

Fromm SA, Lawrence RE, Hurley JH. Fromm SA, et al. Nat Struct Mol Biol. 2020 Nov;27(11):1017-1023. doi: 10.1038/s41594-020-0490-9. Epub 2020 Aug 31. Nat Struct Mol Biol. 2020. PMID: 32868926 Free PMC article.

7

C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.

Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn JHM, Zhen X, Wang G, Ying Z. Wang M, et al. Aging Cell. 2020 Apr;19(4):e13126. doi: 10.1111/acel.13126. Epub 2020 Feb 25. Aging Cell. 2020. PMID: 32100453 Free PMC article.

8

Architecture of human Rag GTPase heterodimers and their complex with mTORC1.

Anandapadamanaban M, Masson GR, Perisic O, Berndt A, Kaufman J, Johnson CM, Santhanam B, Rogala KB, Sabatini DM, Williams RL. Anandapadamanaban M, et al. Science. 2019 Oct 11;366(6462):203-210. doi: 10.1126/science.aax3939. Science. 2019. PMID: 31601764 Free PMC article.

9

Structural basis for the docking of mTORC1 on the lysosomal surface.

Rogala KB, Gu X, Kedir JF, Abu-Remaileh M, Bianchi LF, Bottino AMS, Dueholm R, Niehaus A, Overwijn D, Fils AP, Zhou SX, Leary D, Laqtom NN, Brignole EJ, Sabatini DM. Rogala KB, et al. Science. 2019 Oct 25;366(6464):468-475. doi: 10.1126/science.aay0166. Epub 2019 Oct 10. Science. 2019. PMID: 31601708 Free PMC article.

10

The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity.

Gan L, Seki A, Shen K, Iyer H, Han K, Hayer A, Wollman R, Ge X, Lin JR, Dey G, Talbot WS, Meyer T. Gan L, et al. Nat Cell Biol. 2019 May;21(5):614-626. doi: 10.1038/s41556-019-0321-6. Epub 2019 Apr 29. Nat Cell Biol. 2019. PMID: 31036939 Free PMC article.

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