PubMed for id: 80243

Year	Number of Results
2002	1
2003	1
2004	3
2005	2
2007	1
2009	3
2010	1
2011	1
2012	2
2013	3
2014	3
2015	2
2016	2
2017	5
2018	2
2019	2
2020	4
2021	4
2024	0

1

PREX2 gene's expression in gastric antral epithelial cells of patients with H. pylori infection.

Hedayati MA, Ahmadi S, Servatyari K, Sheikhesmaeili F. Hedayati MA, et al. Arq Gastroenterol. 2021 Jul-Sep;58(3):353-358. doi: 10.1590/S0004-2803.202100000-59. Arq Gastroenterol. 2021. PMID: 34705970 Free article.

2

Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein Facilitates Glioma Progression via Akt and Stat3 Signaling.

Shang J, Li Y, Yin G, Li Z, Jiang L, Bai Q. Shang J, et al. J Mol Neurosci. 2021 Aug;71(8):1674-1682. doi: 10.1007/s12031-021-01883-x. Epub 2021 Jul 28. J Mol Neurosci. 2021. PMID: 34322848

3

Melanoma mystery.

Davis RJ. Davis RJ. Elife. 2017 Jan 19;6:e22662. doi: 10.7554/eLife.22662. Elife. 2017. PMID: 28100393 Free PMC article.

4

Melanoma genome sequencing reveals frequent PREX2 mutations.

Berger MF, Hodis E, Heffernan TP, Deribe YL, Lawrence MS, Protopopov A, Ivanova E, Watson IR, Nickerson E, Ghosh P, Zhang H, Zeid R, Ren X, Cibulskis K, Sivachenko AY, Wagle N, Sucker A, Sougnez C, Onofrio R, Ambrogio L, Auclair D, Fennell T, Carter SL, Drier Y, Stojanov P, Singer MA, Voet D, Jing R, Saksena G, Barretina J, Ramos AH, Pugh TJ, Stransky N, Parkin M, Winckler W, Mahan S, Ardlie K, Baldwin J, Wargo J, Schadendorf D, Meyerson M, Gabriel SB, Golub TR, Wagner SN, Lander ES, Getz G, Chin L, Garraway LA. Berger MF, et al. Nature. 2012 May 9;485(7399):502-6. doi: 10.1038/nature11071. Nature. 2012. PMID: 22622578 Free PMC article.

5

Substrate specificity and recognition is conferred by the pleckstrin homology domain of the Dbl family guanine nucleotide exchange factor P-Rex2.

Joseph RE, Norris FA. Joseph RE, et al. J Biol Chem. 2005 Jul 29;280(30):27508-12. doi: 10.1074/jbc.M412495200. Epub 2005 May 16. J Biol Chem. 2005. PMID: 15897194 Free article.

6

P-REX2, a novel PI-3-kinase sensitive Rac exchange factor.

Rosenfeldt H, Vázquez-Prado J, Gutkind JS. Rosenfeldt H, et al. FEBS Lett. 2004 Aug 13;572(1-3):167-71. doi: 10.1016/j.febslet.2004.06.097. FEBS Lett. 2004. PMID: 15304342 Free article.

7

MiR-637 suppresses melanoma progression through directly targeting P-REX2a and inhibiting PTEN/AKT signaling pathway.

Zhang J, Liu WL, Zhang L, Ge R, He F, Gao TY, Tian Q, Mu X, Chen LH, Chen W, Li X. Zhang J, et al. Cell Mol Biol (Noisy-le-grand). 2018 Aug 30;64(11):50-57. Cell Mol Biol (Noisy-le-grand). 2018. PMID: 30213289

8

P-Rex1 and P-Rex2 RacGEFs and cancer.

Srijakotre N, Man J, Ooms LM, Lucato CM, Ellisdon AM, Mitchell CA. Srijakotre N, et al. Biochem Soc Trans. 2017 Aug 15;45(4):963-77. doi: 10.1042/BST20160269. Epub 2017 Jul 14. Biochem Soc Trans. 2017. PMID: 28710285 Review.

9

Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations.

Horrigan SK, Courville P, Sampey D, Zhou F, Cai S; Reproducibility Project: Cancer Biology. Horrigan SK, et al. Elife. 2017 Jan 19;6:e21634. doi: 10.7554/eLife.21634. Elife. 2017. PMID: 28100394 Free PMC article.

10

p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.

Barrows D, Schoenfeld SM, Hodakoski C, Silkov A, Honig B, Couvillon A, Shymanets A, Nürnberg B, Asara JM, Parsons R. Barrows D, et al. J Biol Chem. 2015 Nov 27;290(48):28915-31. doi: 10.1074/jbc.M115.668244. Epub 2015 Oct 5. J Biol Chem. 2015. PMID: 26438819 Free PMC article.

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