PubMed for id: 7294

Year	Number of Results
1994	2
1996	2
1997	1
1998	1
1999	2
2000	1
2001	1
2002	3
2003	1
2004	2
2005	2
2006	3
2007	1
2008	1
2009	1
2010	3
2011	1
2012	3
2014	1
2015	2
2019	1
2020	1
2021	1
2024	0

1

Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet's disease.

Suzuki N, Nara K, Suzuki T. Suzuki N, et al. Clin Med Res. 2006 Jun;4(2):147-51. doi: 10.3121/cmr.4.2.147. Clin Med Res. 2006. PMID: 16809408 Free PMC article. Review.

2

TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12.

Haire RN, Ohta Y, Lewis JE, Fu SM, Kroisel P, Litman GW. Haire RN, et al. Hum Mol Genet. 1994 Jun;3(6):897-901. doi: 10.1093/hmg/3.6.897. Hum Mol Genet. 1994. PMID: 7951233

3

Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.

Zhong Y, Dong S, Strattan E, Ren L, Butchar JP, Thornton K, Mishra A, Porcu P, Bradshaw JM, Bisconte A, Owens TD, Verner E, Brameld KA, Funk JO, Hill RJ, Johnson AJ, Dubovsky JA. Zhong Y, et al. J Biol Chem. 2015 Mar 6;290(10):5960-78. doi: 10.1074/jbc.M114.614891. Epub 2015 Jan 15. J Biol Chem. 2015. PMID: 25593320 Free PMC article.

4

Evidence of autophosphorylation in Txk: Y91 is an autophosphorylation site.

Kashiwakura J, Suzuki N, Takeno M, Itoh S, Oku T, Sakane T, Nakajin S, Toyoshima S. Kashiwakura J, et al. Biol Pharm Bull. 2002 Jun;25(6):718-21. doi: 10.1248/bpb.25.718. Biol Pharm Bull. 2002. PMID: 12081135 Free article.

5

Txk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon gamma production in human T lymphocytes.

Kashiwakura J, Suzuki N, Nagafuchi H, Takeno M, Takeba Y, Shimoyama Y, Sakane T. Kashiwakura J, et al. J Exp Med. 1999 Oct 18;190(8):1147-54. doi: 10.1084/jem.190.8.1147. J Exp Med. 1999. PMID: 10523612 Free PMC article.

6

A YAC contig spanning a cluster of human type III receptor protein tyrosine kinase genes (PDGFRA-KIT-KDR) in chromosome segment 4q12.

Spritz RA, Strunk KM, Lee ST, Lu-Kuo JM, Ward DC, Le Paslier D, Altherr MR, Dorman TE, Moir DT. Spritz RA, et al. Genomics. 1994 Jul 15;22(2):431-6. doi: 10.1006/geno.1994.1405. Genomics. 1994. PMID: 7528718 Free article.

7

Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.

Sahu N, Venegas AM, Jankovic D, Mitzner W, Gomez-Rodriguez J, Cannons JL, Sommers C, Love P, Sher A, Schwartzberg PL, August A. Sahu N, et al. J Immunol. 2008 Nov 1;181(9):6125-31. doi: 10.4049/jimmunol.181.9.6125. J Immunol. 2008. PMID: 18941202 Free PMC article.

8

Trihydrophobin 1 is a new negative regulator of A-Raf kinase.

Liu W, Shen X, Yang Y, Yin X, Xie J, Yan J, Jiang J, Liu W, Wang H, Sun M, Zheng Y, Gu J. Liu W, et al. J Biol Chem. 2004 Mar 12;279(11):10167-75. doi: 10.1074/jbc.M307994200. Epub 2003 Dec 18. J Biol Chem. 2004. PMID: 14684750 Free article.

9

Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription.

Takeba Y, Nagafuchi H, Takeno M, Kashiwakura J, Suzuki N. Takeba Y, et al. J Immunol. 2002 Mar 1;168(5):2365-70. doi: 10.4049/jimmunol.168.5.2365. J Immunol. 2002. PMID: 11859127

10

Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.

Chamorro M, Czar MJ, Debnath J, Cheng G, Lenardo MJ, Varmus HE, Schwartzberg PL. Chamorro M, et al. BMC Immunol. 2001;2:3. doi: 10.1186/1471-2172-2-3. Epub 2001 May 8. BMC Immunol. 2001. PMID: 11353545 Free PMC article.

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