PubMed for id: 2034

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38335297,38195958,37826874,37463949,37463421,37453673,37449559,37288511,37285480,36934786,36631133,36002380,35732606,35713587,35394128,34678164,34353313,34287062,34250767,34050022,34031851,33966427,33752529,33300499,33114456,33024108,32954526,32652532,32470757,32432822,32219604,32094357,31876943,31185588,31148343,30966832,30836200,30574831,30563765,30340507,30021192,29968905,29859855,29843956,29601261,29446909,29321085,28968430,28448578,28259908,28096303,27765951,27699500,27623205,27596920,27384772,27130043,27119229,27025692,26886654,26883865,26782458,26514359,26368009,26263511,26073780,25966094,25889867,25829424,25730079,25726527,25719580,25569234,25487445,25436804,25338835,25239027,25192290,25109928,24884370,24859386,24813631,24781045,24741025,24070809,24041620,23940778,23716564,23533246,23418310,23361906,23227185,23174107,23090011,22931260,22367913,22113997,21983741,21927022,21925595,21718164,21389259,21217668,21127501,20939709,20595611,20534544,20375133,19955413,19805377,19590888,19481479,19477429,19322701,19010893,18957292,18711622,18508787,18423372,18420194,18378852,18319549,17907154,17417656,16208515,16098466,15652356,15598469,14966910,38365849,37783786,37473874,37327294,37108194,36728187,36482296,36252650,35978075,35596131,35395428,35216458,35191554,35102545,35054927,34824343,34461182,34285132,33760204,33273561,33012513,32718338,32718321,32681351,32185192,32157720,32142369,31900259,31794514,31266772,30917010,30670058,30655088,30617181,30536571,30487161,30468780,30429208,30267660,30144808,30135144,29845228,29577908,29357946,29281714,29263346,29247885,29206844,29176561,29172931,29091312,29026132,28951458,28900259,28840922,28709643,28653893,28624448,28614393,28613249,28544376,28476028,28394947,28233034,28153790,28079892,27902963,27883285,27862077,27809360,27793037,27692362,27663442,27500357,27465550,27442627,27413748,27276678,27270657,27244898,26898802,26892680,26880584,26851078,26849233,26846782,26826018,26810190,26783937,26707870,26647960,26531845,26439684,26432405,26402839,26307391,26305551,26296885,25805230,25792003,25715026,25574837,25565665,25544768,25520177,25501874,25489981,25417700,25396735,25244496,25218350,25216407,25085245,25046225,24850901,24825851,24726658,24705306,24704828,24656769,24607784,24513612,24464808,24394537,24394419,24368849,24363272,24324596,23958427,23886153,23873332,23852087,23588703,23492195,23479510,23473032,23455322,23447580,23434853,23378636,23375698,23303559,23194660,22894905,22869144,22673574,22595196,22537539,22402494,22277691,22247019,21985026,21946204,21841824,21840298,21695080,21637285,21610325,21571835,21512133,21382346,21327823,21263150,20965423,20961960,20807755,20632821,20559438,20559021,20513003,20395290,20354189,20204822,20158574,20039838,20032376,20015878,19914104,19903792,19706526,19660915,19541651,19436307,19129502,19077391,19030186,18650473,18024825,17998805,17718430,17570486,17562539,17526729,17437013,17324924,17097563,16826581,16740701,16284786,16263938,15964822,15217953,15192019,15039136,14985465,14645546,12697324,12209691,12123724,38287821,38263248,37371055,36175619,36053046,34339013,33865222,33244167,33182300,33049075,32965071,32813008,32739800,32515984,32476798,31366501,31310363,31267758,31189709,30962349,30784290,30553971,30478339,29948390,29784889,29629903,28993199,28599281,28302031,28196140,28167508,28115494,28112200,27934882,27686097,27524242,27323688,27001847,27001172,26880412,26842802,26735578,26408396,26148512,25936862,25912138,25831463,25689462,25627682,25557012,25391657,24938788,24806027,24661907,24644426,24451260,24434023,24423936,24378640,24288553,24176785,24037341,23946285,23881929,23796364,23750001,23335846,23334958,23333640,23212661,23063455,22452996,22103974,22068265,21984395,21888897,21483406,21131975,21109953,21081659,21073737,21030426,20856199,20824203,20551700,20416395,20224786,19845609,19837976,19483472,19401348,19386601,19238077,19208626,19080330,18945681,18055454,17967880,17852557,17684156,17555795,17285230,17220275,17140440,16920734,16554418,15240563,14744852,14668441,14512791,11331613,11313887,10878807,10353251,38501098,34346275,34128478,33914705,32593213,32291411,30431439,29422508,29035368,28963486,28893800,28436035,27412013,26825173,26572826,26558437,26510548,26160453,25758454,25271810,25108527,24998849,24371328,24356968,23911400,23840432,23478175,23042097,22966206,22093255,22090111,21042786,20496369,20028863,19287200,19021062,18728663,18372249,17452775,16760477,16407130,16278385,16181639,15653678,14691554,12823854,10202154,34931765,32699137,32513733,30962421,28720067,26973243,26837714,26342197,25963717,25043030,24503013,24353279,23222716,22684009,22678294,22075993,21869830,21362301,21057546,20964835,20304964,18442887,17477366,16885164,15247232,15156561,14556007,12588875,11292862,11018023,34325467,32461361,29483579,26642852,26500060,25517638,25500545,25440060,25187556,23897427,23785149,21658608,21512126,21257819,20978319,19498162,19252526,18625704,18077449,17495954,17024177,15474027,11823643,11573933,9000051,33591636,288480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Results by year

Year	Number of Results
1996	2
1997	4
1998	1
1999	2
2000	3
2001	4
2002	6
2003	11
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2006	12
2007	25
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2024	6

624 results

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Page 1

Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders.

Lawrence ES, Gu W, Bohlender RJ, Anza-Ramirez C, Cole AM, Yu JJ, Hu H, Heinrich EC, O'Brien KA, Vasquez CA, Cowan QT, Bruck PT, Mercader K, Alotaibi M, Long T, Hall JE, Moya EA, Bauk MA, Reeves JJ, Kong MC, Salem RM, Vizcardo-Galindo G, Macarlupu JL, Figueroa-Mujíca R, Bermudez D, Corante N, Gaio E, Fox KP, Salomaa V, Havulinna AS, Murray AJ, Malhotra A, Powel FL, Jain M, Komor AC, Cavalleri GL, Huff CD, Villafuerte FC, Simonson TS. Lawrence ES, et al. Sci Adv. 2024 Feb 9;10(6):eadj5661. doi: 10.1126/sciadv.adj5661. Epub 2024 Feb 9. Sci Adv. 2024. PMID: 38335297 Free PMC article.

EPAS1-mutated paragangliomas associated with haemoglobin disorders.

Mancini M, Buffet A, Porte B, Amar L, Lussey-Lepoutre C, Crinière L, Baudin E, Meatchi T, Gimenez-Roqueplo AP, Favier J, Burnichon N. Mancini M, et al. Br J Haematol. 2024 Mar;204(3):1054-1060. doi: 10.1111/bjh.19278. Epub 2024 Jan 9. Br J Haematol. 2024. PMID: 38195958

Hypoxia-inducible factor 2α protein and mRNA expression correlate with histomorphological features in clear cell renal cell carcinoma.

Pham T, Ohe C, Yoshida T, Nakamoto T, Kinoshita H, Tsuta K. Pham T, et al. Pathol Res Pract. 2023 Nov;251:154841. doi: 10.1016/j.prp.2023.154841. Epub 2023 Oct 2. Pathol Res Pract. 2023. PMID: 37826874

Cytoplasmic HIF-2α as tissue biomarker to identify metastatic sympathetic paraganglioma.

Karakaya S, Gunnesson L, Elias E, Martos-Salvo P, Robledo M, Nilsson O, Wängberg B, Abel F, Påhlman S, Muth A, Mohlin S. Karakaya S, et al. Sci Rep. 2023 Jul 18;13(1):11588. doi: 10.1038/s41598-023-38606-8. Sci Rep. 2023. PMID: 37463949 Free PMC article.

High-Altitude Andean H194R HIF2A Allele Is a Hypomorphic Allele.

Jorgensen K, Song D, Weinstein J, Garcia OA, Pearson LN, Inclán M, Rivera-Chira M, León-Velarde F, Kiyamu M, Brutsaert TD, Bigham AW, Lee FS. Jorgensen K, et al. Mol Biol Evol. 2023 Jul 5;40(7):msad162. doi: 10.1093/molbev/msad162. Mol Biol Evol. 2023. PMID: 37463421 Free PMC article.

A novel HIF2A mutation causes dyslipidemia and promotes hepatic lipid accumulation.

Gao F, Yao Q, Zhu J, Chen W, Feng X, Feng B, Wu J, Pacak K, Rosenblum J, Yu J, Zhuang Z, Cao H, Li L. Gao F, et al. Pharmacol Res. 2023 Aug;194:106851. doi: 10.1016/j.phrs.2023.106851. Epub 2023 Jul 13. Pharmacol Res. 2023. PMID: 37453673 Free article.

Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2.

Figg WD Jr, Fiorini G, Chowdhury R, Nakashima Y, Tumber A, McDonough MA, Schofield CJ. Figg WD Jr, et al. Proteins. 2023 Nov;91(11):1510-1524. doi: 10.1002/prot.26541. Epub 2023 Jul 14. Proteins. 2023. PMID: 37449559 Free PMC article.

On either side of homeostasis: EPAS1 gain- and loss-offunction mutations.

Prchal JT, Semenza GL. Prchal JT, et al. Haematologica. 2023 Oct 1;108(10):2564-2565. doi: 10.3324/haematol.2023.283285. Haematologica. 2023. PMID: 37288511 Free PMC article. No abstract available.

Somatic EPAS1 Variants in Pheochromocytoma and Paraganglioma in Patients With Sickle Cell Disease.

White G, Nonaka D, Chung TT, Oakey RJ, Izatt L. White G, et al. J Clin Endocrinol Metab. 2023 Nov 17;108(12):3302-3310. doi: 10.1210/clinem/dgad311. J Clin Endocrinol Metab. 2023. PMID: 37285480 Free PMC article.

EPAS1 resistance to miRNA-based regulation contributes to prolonged expression of HIF-2 during hypoxia in human endothelial cells.

Jaśkiewicz M, Moszyńska A, Gebert M, Collawn JF, Bartoszewski R. Jaśkiewicz M, et al. Gene. 2023 Jun 5;868:147376. doi: 10.1016/j.gene.2023.147376. Epub 2023 Mar 18. Gene. 2023. PMID: 36934786 Free article.

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