PubMed for id: 20271

Year	Number of Results
1993	1
1995	1
1996	1
1999	1
2000	2
2001	2
2002	4
2003	3
2004	6
2005	10
2006	11
2007	12
2008	6
2009	7
2010	14
2011	17
2012	14
2013	8
2014	15
2015	8
2016	9
2017	8
2018	11
2019	10
2020	12
2021	7
2022	2
2023	5
2024	3

1

Mannitol and hyponatremia regulate cardiac ventricular conduction in the context of sodium channel loss of function.

Blair GA, Wu X, Bain C, Warren M, Hoeker GS, Poelzing S. Blair GA, et al. Am J Physiol Heart Circ Physiol. 2024 Mar 1;326(3):H724-H734. doi: 10.1152/ajpheart.00211.2023. Epub 2024 Jan 12. Am J Physiol Heart Circ Physiol. 2024. PMID: 38214908 Free article.

2

In Vivo Base Editing of Scn5a Rescues Type 3 Long QT Syndrome in Mice.

Qi M, Ma S, Liu J, Liu X, Wei J, Lu WJ, Zhang S, Chang Y, Zhang Y, Zhong K, Yan Y, Zhu M, Song Y, Chen Y, Hao G, Wang J, Wang L, Lee AS, Chen X, Wang Y, Lan F. Qi M, et al. Circulation. 2024 Jan 23;149(4):317-329. doi: 10.1161/CIRCULATIONAHA.123.065624. Epub 2023 Nov 15. Circulation. 2024. PMID: 37965733

3

SUMOylation of the cardiac sodium channel Na_V1.5 modifies inward current and cardiac excitability.

Yoon JY, Greiner AM, Jacobs JS, Kim YR, Rasmussen TP, Kutschke WJ, Matasic DS, Vikram A, Gaddam RR, Mehdi H, Irani K, London B. Yoon JY, et al. Heart Rhythm. 2023 Nov;20(11):1548-1557. doi: 10.1016/j.hrthm.2023.07.067. Epub 2023 Aug 3. Heart Rhythm. 2023. PMID: 37543305

4

Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide.

O'Reilly M, Sommerfeld LC, O'Shea C, Broadway-Stringer S, Andaleeb S, Reyat JS, Kabir SN, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin BV, Holmes AP, Kirchhof P, Fabritz L. O'Reilly M, et al. Europace. 2023 Mar 30;25(3):1152-1161. doi: 10.1093/europace/euac218. Europace. 2023. PMID: 36504385 Free PMC article.

5

Association between SCN5A R225Q variant and dilated cardiomyopathy: potential role of intracellular pH and WNT/β-catenin pathway.

Hu J, Yang K, Zhao Y, Wei Z, Yang L, Gao R, Wu Y, Xu L, Xu S, Hu K, Sun A, Ge J. Hu J, et al. J Med Genet. 2022 Dec;59(12):1139-1149. doi: 10.1136/jmedgenet-2021-108396. Epub 2022 Jun 14. J Med Genet. 2022. PMID: 35701104

6

Phospho-ablation of cardiac sodium channel Na_v1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity.

Dewal RS, Greer-Short A, Lane C, Nirengi S, Manzano PA, Hernández-Saavedra D, Wright KR, Nassal D, Baer LA, Mohler PJ, Hund TJ, Stanford KI. Dewal RS, et al. Int J Obes (Lond). 2021 Apr;45(4):795-807. doi: 10.1038/s41366-021-00742-4. Epub 2021 Jan 26. Int J Obes (Lond). 2021. PMID: 33500550 Free PMC article.

7

Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice.

Comelli M, Meo M, Cervantes DO, Pizzo E, Plosker A, Mohler PJ, Hund TJ, Jacobson JT, Meste O, Rota M. Comelli M, et al. Am J Physiol Heart Circ Physiol. 2020 Oct 1;319(4):H893-H905. doi: 10.1152/ajpheart.00379.2020. Epub 2020 Sep 4. Am J Physiol Heart Circ Physiol. 2020. PMID: 32886003 Free PMC article.

8

Autonomic modulation of the electrical substrate in mice haploinsufficient for cardiac sodium channels: a model of the Brugada syndrome.

Finlay M, Bhar-Amato J, Ng KE, Santos D, Orini M, Vyas V, Taggart P, Grace AA, Huang CL, Lambiase PD, Tinker A. Finlay M, et al. Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C576-C583. doi: 10.1152/ajpcell.00028.2019. Epub 2019 Jul 10. Am J Physiol Cell Physiol. 2019. PMID: 31291141 Free PMC article.

9

SCN5A variant R222Q generated abnormal changes in cardiac sodium current and action potentials in murine myocytes and Purkinje cells.

Daniel LL, Yang T, Kroncke B, Hall L, Stroud D, Roden DM. Daniel LL, et al. Heart Rhythm. 2019 Nov;16(11):1676-1685. doi: 10.1016/j.hrthm.2019.05.017. Epub 2019 May 21. Heart Rhythm. 2019. PMID: 31125670 Free PMC article.

10

CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias.

Pang PD, Alsina KM, Cao S, Koushik AB, Wehrens XHT, Cooper TA. Pang PD, et al. J Am Heart Assoc. 2018 Oct 2;7(19):e010393. doi: 10.1161/JAHA.118.010393. J Am Heart Assoc. 2018. PMID: 30371314 Free PMC article.

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