Chromosomal mapping of two RBP-J-related genes: Kyo-T and RBP-L

S Tani; M Taniwaki; Y Taniguchi; S Minoguchi; K Kuroda; H Han; T Aoki; S Miyatake; N Hashimoto; T Honjo

doi:10.1007/s100380050112

Chromosomal mapping of two RBP-J-related genes: Kyo-T and RBP-L

J Hum Genet. 1999;44(1):73-5. doi: 10.1007/s100380050112.

Authors

S Tani¹, M Taniwaki, Y Taniguchi, S Minoguchi, K Kuroda, H Han, T Aoki, S Miyatake, N Hashimoto, T Honjo

Affiliation

¹ Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Japan.

PMID: 9929984
DOI: 10.1007/s100380050112

Abstract

We have recently isolated two genes encoding proteins which have either homology or affinity to RBP-J, a transcription factor involved in Notch signaling. Kyo-T interacts with RBP-J and possibly regulates the function of RBP-J. RBP-L has a highly homologous region with RBP-J but the function of RBP-L is unknown. Fluorescence in situ hybridization analysis of human metaphase chromosomes localized Kyo-T and RBP-L to Xq26 and 20q12-13.1, respectively.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 20 / genetics
DNA, Complementary / genetics
DNA-Binding Proteins / genetics*
Humans
In Situ Hybridization, Fluorescence
Intracellular Signaling Peptides and Proteins
LIM Domain Proteins
Muscle Proteins*
Transcription Factors / genetics*
X Chromosome / genetics

Substances

DNA, Complementary
DNA-Binding Proteins
FHL1 protein, human
Intracellular Signaling Peptides and Proteins
LIM Domain Proteins
Muscle Proteins
RBPJL protein, human
Transcription Factors