Mapping of human DNA-binding nuclear protein (NP220) to chromosome band 2p13.1-p13.2 and its relation to matrin 3

K Okumara; M Nogami; Y Matsushima; K Matsumura; K Nakamura; H Taguchi; Y Kitagawa

doi:10.1271/bbb.62.1640

Mapping of human DNA-binding nuclear protein (NP220) to chromosome band 2p13.1-p13.2 and its relation to matrin 3

Biosci Biotechnol Biochem. 1998 Aug;62(8):1640-2. doi: 10.1271/bbb.62.1640.

Authors

K Okumara¹, M Nogami, Y Matsushima, K Matsumura, K Nakamura, H Taguchi, Y Kitagawa

Affiliation

¹ Laboratory of Biological Chemistry, Faculty of Bioresouces, Mie University, Japan.

PMID: 9757574
DOI: 10.1271/bbb.62.1640

Abstract

Human NP220 (hNP220) is a novel DNA-binding nuclear protein, which has an arginine/serine-rich motif and polypyrimidine tract-binding motif, and NP220s and matrin 3 are thought to form a novel family of nuclear proteins. We have determined a chromosomal localization of the cDNA encoding human NP220 to 2p13.1-p13.2 by using fluorescence in situ hybridization. Human matrin 3 cDNA was mapped to chromosomes 1p13.1-p21.1 and 5q31.3, demonstrating that these novel nuclear proteins with similar functions are on different chromosomes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosome Banding
Chromosome Mapping*
Chromosomes, Human, Pair 2 / chemistry*
Chromosomes, Human, Pair 2 / physiology
DNA Probes / chemistry
DNA, Complementary / chemistry
DNA-Binding Proteins / chemistry
DNA-Binding Proteins / genetics*
Humans
Image Processing, Computer-Assisted
In Situ Hybridization, Fluorescence
Nuclear Proteins / chemistry
Nuclear Proteins / genetics*
RNA-Binding Proteins

Substances

DNA Probes
DNA, Complementary
DNA-Binding Proteins
Nuclear Proteins
RNA-Binding Proteins
matrin 3, rat