A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2

H Tarnasky; D Gill; S Murthy; X Shao; D J Demetrick; F A van der Hoorn

doi:10.1159/000014990

A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2

Cytogenet Cell Genet. 1998;81(1):65-7. doi: 10.1159/000014990.

Authors

H Tarnasky¹, D Gill, S Murthy, X Shao, D J Demetrick, F A van der Hoorn

Affiliation

¹ Department of Medical Biochemistry, Southern Alberta Cancer Research Centre, University of Calgary, Calgary, Alberta (Canada).

PMID: 9691178
DOI: 10.1159/000014990

Abstract

The product of the spermatid-specific rat SPAG4 gene interacts specifically with the major 27-kDa outer dense fiber protein ODF27 in elongating spermatids. In this study we isolated the human homolog of the spermatid-specific rat SPAG4 gene and mapped it by fluorescence in situ hybridization to chromosome 20q11.2.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Carrier Proteins*
Chromosome Mapping
Chromosomes, Human, Pair 20 / genetics*
DNA Probes / genetics
DNA, Complementary / genetics
Gene Library
Genes / genetics*
Heat-Shock Proteins*
Humans
In Situ Hybridization, Fluorescence
Male
Membrane Proteins
Molecular Sequence Data
Proteins / genetics
Proteins / metabolism*
Restriction Mapping
Sequence Homology, Nucleic Acid
Testis / metabolism*

Substances

Carrier Proteins
DNA Probes
DNA, Complementary
Heat-Shock Proteins
Membrane Proteins
ODF1 protein, human
Odf1 protein, rat
Proteins
SPAG4 protein, human
Spag4 protein, rat

Associated data

GENBANK/AF043344
GENBANK/AF043345