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Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis.
Clin Immunol Immunopathol. 1997 Nov;85(2):195-201. doi: 10.1006/clin.1997.4424.
Clin Immunol Immunopathol. 1997.
PMID: 9344703
Free article.
CD4 cross-linking (CD4XL) induces RAS activation and tumor necrosis factor-alpha secretion in CD4+ T cells.
Tamma SM, Chirmule N, Yagura H, Oyaizu N, Kalyanaraman V, Pahwa S.
Tamma SM, et al.
Blood. 1997 Aug 15;90(4):1588-93.
Blood. 1997.
PMID: 9269777
Free article.
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