Abstract
Zonadhesin is a recently discovered sperm membrane protein that binds to the extracellular matrix of the egg in a species-specific manner. The gene for zonadhesin maps to chromosome 5 in the mouse (Zan) and to chromosome 7 in the human (ZAN) in a position near the gene for the egg extracellular matrix protein ZP3.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Chromosome Mapping
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Chromosomes, Human, Pair 7 / genetics
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Cricetinae
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DNA Primers / genetics
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Egg Proteins / genetics
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Female
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Humans
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In Situ Hybridization, Fluorescence
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Male
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Membrane Glycoproteins / genetics
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Membrane Proteins / genetics*
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Mice
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Mice, Inbred C57BL
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Molecular Sequence Data
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Muridae
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Receptors, Cell Surface*
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Sequence Homology, Amino Acid
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Species Specificity
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Spermatozoa / metabolism
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Zona Pellucida Glycoproteins
Substances
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DNA Primers
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Egg Proteins
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Membrane Glycoproteins
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Membrane Proteins
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Receptors, Cell Surface
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ZP3 protein, human
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Zona Pellucida Glycoproteins
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Zp3 protein, mouse
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zonadhesin
Associated data
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GENBANK/U83190
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GENBANK/U83191