FISH mapping of centromere protein C (CENPC) on human chromosome 4q31-->q21

Y Xie; H H Heng

doi:10.1159/000134412

FISH mapping of centromere protein C (CENPC) on human chromosome 4q31-->q21

Cytogenet Cell Genet. 1996;74(3):192-3. doi: 10.1159/000134412.

Authors

Y Xie¹, H H Heng

Affiliation

¹ Biology Department, Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong. boyxie@usthk.ust.hk

PMID: 8941372
DOI: 10.1159/000134412

Abstract

Centromere protein C (CENP-C), a human centromere autoantigen, is a component of the inner kinetochore plate. CENP-C is required for maintaining proper kinetochore size and a timely transition to anaphase. In this study using fluorescence in situ hybridization to metaphase chromosomes, the human CENP-C gene (CENPC) was mapped on chromosome 4, region q13-->q21.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosomal Proteins, Non-Histone / genetics*
Chromosome Mapping*
Chromosomes, Human, Pair 4 / genetics*
Genes / genetics
Humans
In Situ Hybridization, Fluorescence

Substances

Chromosomal Proteins, Non-Histone
centromere protein C