Nucleotide sequence of exons 5 to 9 of the p53 tumour-suppressor gene of the horse (Equus caballus)

DNA Seq. 1996;6(3):185-7. doi: 10.3109/10425179609010208.

Abstract

An evolutionary conserved 1.3 kb fragment corresponding to the horse p53 tumour suppressor gene was PCR amplified, cloned and the nucleotide sequence determined. The p53 fragment encoded exons 5 to 9 and the intervening introns. The nucleotide sequence and the predicted aminoacid sequence showed a high level of homology with human and donkey p53 sequences.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • Conserved Sequence / genetics
  • Genes, p53 / genetics*
  • Horses / genetics*
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Homology, Nucleic Acid
  • Tumor Suppressor Protein p53 / chemistry

Substances

  • Tumor Suppressor Protein p53

Associated data

  • GENBANK/U37120