Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I

N Yamazaki; Y Shinohara; A Shima; Y Yamanaka; H Terada

doi:10.1016/0167-4781(96)00069-3

Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I

Biochim Biophys Acta. 1996 Jun 7;1307(2):157-61. doi: 10.1016/0167-4781(96)00069-3.

Authors

N Yamazaki¹, Y Shinohara, A Shima, Y Yamanaka, H Terada

Affiliation

¹ Faculty of Pharmaceutical Sciences, University of Tokushima, Japan.

PMID: 8679700
DOI: 10.1016/0167-4781(96)00069-3

Abstract

With a cDNA probe encoding rat muscle type carnitine palmitoyltransferase I (CPTI), we isolated cDNA and genomic clones encoding the human homologue and deduced the primary structure of human muscle type CPTI. By Northern analysis, we confirmed the dominant expression of this isoform in heart and skeletal muscle.

MeSH terms

Amino Acid Sequence
Animals
Base Sequence
Carnitine O-Palmitoyltransferase / genetics*
DNA, Complementary
Humans
Isoenzymes / genetics*
Molecular Sequence Data
Muscle, Skeletal / enzymology*
Myocardium / enzymology*
Rats
Sequence Homology, Amino Acid

Substances

DNA, Complementary
Isoenzymes
Carnitine O-Palmitoyltransferase

Associated data

GENBANK/D87812