Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: strategies to overcome drug resistance development

Med Res Rev. 1996 Mar;16(2):125-57. doi: 10.1002/(SICI)1098-1128(199603)16:2<125::AID-MED1>3.0.CO;2-2.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / drug therapy*
  • Antiviral Agents / therapeutic use*
  • Clinical Trials as Topic
  • Drug Resistance, Microbial
  • HIV Reverse Transcriptase
  • HIV-1 / drug effects
  • HIV-1 / enzymology
  • Humans
  • Nucleosides / therapeutic use
  • RNA-Directed DNA Polymerase / drug effects*
  • RNA-Directed DNA Polymerase / metabolism
  • Reverse Transcriptase Inhibitors / therapeutic use*
  • Structure-Activity Relationship

Substances

  • Antiviral Agents
  • Nucleosides
  • Reverse Transcriptase Inhibitors
  • HIV Reverse Transcriptase
  • RNA-Directed DNA Polymerase