Stability of bupivacaine hydrochloride and hydromorphone hydrochloride during simulated epidural coadministration

C Christen; C E Johnson; J R Walters

doi:10.1093/ajhp/53.2.170

Stability of bupivacaine hydrochloride and hydromorphone hydrochloride during simulated epidural coadministration

Am J Health Syst Pharm. 1996 Jan 15;53(2):170-3. doi: 10.1093/ajhp/53.2.170.

Authors

C Christen¹, C E Johnson, J R Walters

Affiliation

¹ Gynecology/Oncology and Adult Acute Pain Service, University of Michigan, Ann Arbor, USA.

PMID: 8653484
DOI: 10.1093/ajhp/53.2.170

Abstract

Bupivacaine hydrochloride 625 and 1250 micrograms/mL and hydromorphone hydrochloride 20 and 100 micrograms/mL in 0.9% sodium chloride injection were stable and compatible for up to 72 hours under fluorescent light when stored in polyvinyl chloride containers at 24 degrees C.

MeSH terms

Analgesics, Opioid / administration & dosage
Analgesics, Opioid / chemistry*
Anesthesia, Epidural
Anesthetics, Local / administration & dosage
Anesthetics, Local / chemistry*
Bupivacaine / administration & dosage
Bupivacaine / chemistry*
Drug Combinations
Drug Stability
Hydromorphone / administration & dosage
Hydromorphone / chemistry*
Pain Measurement

Substances

Analgesics, Opioid
Anesthetics, Local
Drug Combinations
Hydromorphone
Bupivacaine