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1: Yeast. 1995 Sep 30;11(12):1179-86.Links

The sequence of 24.3 kb from chromosome X reveals five complete open reading frames, all of which correspond to new genes, and a tandem insertion of a Ty1 transposon.

Zagulski M, Babinska B, Gromadka R, Migdalski A, Rytka J, Sulicka J, Herbert CJ.

Centre de Genetique Moleculaire, lUniversite Pierre et Marie Curie, Gif-sur-Yvette, France.

We have determined the complete nucleotide sequence of a 24.3 kb segment from chromosome X carried by the cosmid pEJ103. The sequence encodes five complete open reading frames (ORFs), none of which correspond to previously described genes; however, four of these ORFs display interesting similarities with sequences present in the databanks. The sequence also contains a tandem insertion of a Ty1 element. An investigation of the Ty1 polymorphism in other strains has revealed that the original insertion occurred within an ORF. Finally, the structure of the Ty1 repeat suggests a mechanism by which it may have been generated.

PMID: 8619316 [PubMed - indexed for MEDLINE]

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