Midkine gene (MDK), a gene for prenatal differentiation and neuroregulation, maps to band 11p11.2 by fluorescence in situ hybridization

Genomics. 1993 Aug;17(2):514-5. doi: 10.1006/geno.1993.1359.

Abstract

Midkine (MDK) is a retinoic acid-responsive gene concerned with prenatal development and neurite growth. We mapped the gene to band p11.2 of chromosome 11 through fluorescence in situ hybridization analysis and using a 4.5-kb fragment of its human genomic DNA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carrier Proteins / genetics*
  • Cell Differentiation / genetics
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 11*
  • Cytokines*
  • DNA / analysis
  • DNA / genetics
  • Embryonic and Fetal Development*
  • Female
  • Humans
  • In Situ Hybridization, Fluorescence
  • Karyotyping
  • Midkine
  • Nervous System / embryology*
  • Placenta / metabolism
  • Pregnancy

Substances

  • Carrier Proteins
  • Cytokines
  • Midkine
  • DNA