Assignment of the phosducin (PDC) gene to human chromosome 1q25-1q32.1 by somatic cell hybridization and in situ hybridization

Genomics. 1993 Nov;18(2):426-8. doi: 10.1006/geno.1993.1490.

Abstract

Phosducin is a soluble photoreceptor phosphoprotein that probably modulates phototransduction in the retina and thus qualifies as a potential candidate gene for retinitis pigmentosa. Using both human/mouse somatic cell hybrids and in situ hybridization to human metaphase chromosomes, we have mapped this gene to chromosome 1q25-1q32.1.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 1*
  • Eye Proteins / genetics*
  • GTP-Binding Protein Regulators
  • Humans
  • Hybrid Cells
  • In Situ Hybridization
  • Mice
  • Phosphoproteins / genetics*

Substances

  • Eye Proteins
  • GTP-Binding Protein Regulators
  • Phosphoproteins
  • phosducin