Cloning of CRP2, a novel member of the cysteine-rich protein family with two repeats of an unusual LIM/double zinc-finger motif

I Okano; T Yamamoto; A Kaji; T Kimura; K Mizuno; T Nakamura

doi:10.1016/0014-5793(93)80373-3

Cloning of CRP2, a novel member of the cysteine-rich protein family with two repeats of an unusual LIM/double zinc-finger motif

FEBS Lett. 1993 Oct 25;333(1-2):51-5. doi: 10.1016/0014-5793(93)80373-3.

Authors

I Okano¹, T Yamamoto, A Kaji, T Kimura, K Mizuno, T Nakamura

Affiliation

¹ Department of Biology, Faculty of Science, Kyushu University, Fukuoka, Japan.

PMID: 8224170
DOI: 10.1016/0014-5793(93)80373-3

Abstract

The cDNA coding for a novel member of the cysteine-rich protein family was isolated from a rat brain cDNA library. It encodes a protein, denoted cysteine-rich protein 2 (CRP2), of 208 amino acid residues containing two tandem repeats of an unusual LIM/double zinc-finger-like motif. The ubiquitous tissue distribution and high level of expression of CRP2 mRNA suggest an important role for CRP2 in cell functions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
CCAAT-Enhancer-Binding Proteins
Cloning, Molecular
DNA
DNA-Binding Proteins / chemistry
DNA-Binding Proteins / genetics*
Humans
Male
Molecular Sequence Data
Nuclear Proteins / chemistry
Nuclear Proteins / genetics*
Polymerase Chain Reaction
Rats
Rats, Wistar
Restriction Mapping
Sequence Homology, Amino Acid
Tissue Distribution
Zinc Fingers*

Substances

CCAAT-Enhancer-Binding Proteins
DNA-Binding Proteins
Nuclear Proteins
DNA

Associated data

GENBANK/D17512