Sequences of the cobalamin biosynthetic genes cobK...[Gene. 1994]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Gene. 1994 May 27;143(1):91-3. Links

Sequences of the cobalamin biosynthetic genes cobK, cobL and cobM from Rhodococcus sp. NI86/21.

De Mot R, Nagy I, Schoofs G, Vanderleyden J.

F.A. Janssens Laboratory of Genetics, Catholic University of Leuven, Heverlee, Belgium.

Sequence analysis of a 5753-bp genomic fragment of Rhodococcus sp. NI86/21 revealed the presence of three homologues of known cobalamin biosynthetic genes. One of these genes encodes a protein showing strong homology with the precorrin-6x reductase (CobK) of Pseudomonas denitrificans. In addition, the rhodococcal homologue of the corrin methyltransferases, CobM from P. denitrificans and CbiF from Salmonella typhimurium, was identified. The protein deduced from a third Rhodococcus gene aligns well with CobL of P. denitrificans and with the protein pair CbiE/CbiT of S. typhimurium, which are involved in corrin methylation and decarboxylation.

PMID: 8200543 [PubMed - indexed for MEDLINE]

Anaerobic growth of Paracoccus denitrificans requires cobalamin: characterization of cobK and cobJ genes. [J Bacteriol. 1999]
Precorrin-6x reductase from Pseudomonas denitrificans: purification and characterization of the enzyme and identification of the structural gene. [J Bacteriol. 1992]
Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product. [J Bacteriol. 1992]
Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid. [J Bacteriol. 1990]
ReviewBiosynthesis of cobalamin (vitamin B12): a bacterial conundrum. [Cell Mol Life Sci. 2000]

Recent Activity

Clear Turn Off

Sequences of the cobalamin biosynthetic genes cobK, cobL and cobM from Rhodococcus sp. NI8...Sequences of the cobalamin biosynthetic genes cobK, cobL and cobM from Rhodococcus sp. NI86/21.

Display Show

Sequences of the cobalamin biosynthetic genes cobK, cobL and cobM from Rhodococcus sp. NI86/21.

Related Articles

Recent Activity