The cDNA sequence of beef heart CII-3, a membrane-intrinsic subunit of succinate-ubiquinone oxidoreductase

Biochim Biophys Acta. 1994 Nov 1;1188(1-2):162-6. doi: 10.1016/0005-2728(94)90035-3.

Abstract

We provide the first full-length cDNA and amino acid sequences for beef heart CII-3, one of two hydrophobic subunits that bind succinate dehydrogenase to the mitochondrial inner membrane to form succinate-ubiquinone oxidoreductase (EC 1.3.99.1). Other low molecular weight proteins present in preparations of the isolated complex, including three possible forms of the second anchor polypeptide CII-4, have been identified by amino terminal sequencing.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cattle
  • DNA, Complementary / analysis*
  • Electron Transport Complex II
  • Mitochondria, Heart / enzymology*
  • Mitochondria, Heart / metabolism
  • Molecular Sequence Data
  • Multienzyme Complexes / chemistry
  • Multienzyme Complexes / genetics*
  • Oxidoreductases / chemistry
  • Oxidoreductases / genetics*
  • Succinate Dehydrogenase / chemistry
  • Succinate Dehydrogenase / genetics*
  • Succinate Dehydrogenase / metabolism

Substances

  • DNA, Complementary
  • Multienzyme Complexes
  • Oxidoreductases
  • Electron Transport Complex II
  • Succinate Dehydrogenase

Associated data

  • GENBANK/S74803