Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization

J van Hengel; F Nollet; G Berx; N van Roy; F Speleman; F van Roy

doi:10.1159/000133994

Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization

Cytogenet Cell Genet. 1995;70(1-2):68-70. doi: 10.1159/000133994.

Authors

J van Hengel¹, F Nollet, G Berx, N van Roy, F Speleman, F van Roy

Affiliation

¹ Laboratory of Molecular Biology, University of Ghent, Belgium.

PMID: 7736793
DOI: 10.1159/000133994

Abstract

The human beta-catenin gene (CTNNB1) has been localized to 3p22-->p21.3 by fluorescence in situ hybridization. Recent studies have suggested the presence of one or more tumor suppressor genes on the short arm of chromosome 3. This raises the possibility that CTNNB1, for which important features are already known, is involved in tumor progression.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 3*
Cytoskeletal Proteins / genetics*
Humans
In Situ Hybridization, Fluorescence
Microscopy, Fluorescence
Molecular Sequence Data
Trans-Activators*
beta Catenin

Substances

CTNNB1 protein, human
Cytoskeletal Proteins
Trans-Activators
beta Catenin