Evolutionary relations among vertebrate muscle-typ...[Mol Mar Biol Biotechnol. 1995]

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1: Mol Mar Biol Biotechnol. 1995 Sep;4(3):224-31.Links

Evolutionary relations among vertebrate muscle-type lactate dehydrogenases.

Quattro JM, Pollock DD, Powell M, Woods HA, Powers DA.

Department of Biology, University of South Carolina, Columbia 29208, USA.

Gene duplication has produced two lactate dehydrogenase (LDH) isozymes, LDH-A and LDH-B, that are found in essentially all vertebrates. On the basis of the biochemical properties of the LDH-A and LDH-B isozymes, it has been suggested that each locus is orthologous among all vertebrates. However, phylogenetic studies have not supported a common evolutionary history among the LDH-A isozymes, particularly when those from lower vertebrates are examined. We present here the sequence of a muscle-type LDH from Fundulus heteroclitus, a teleost fish for which the LDH-B sequence has been determined and shown to be unrelated phylogenetically to tetrapod LDH-A isozymes. Although the sequence of the teleost muscle LDH shares certain features with the LDH-A of tetrapods, phylogenetic analyses do not support an orthologous relation among the LDH-A isozymes of teleost fish and tetrapod vertebrates.

PMID: 7670598 [PubMed - indexed for MEDLINE]

Sequence analysis of teleost retina-specific lactate dehydrogenase C: evolutionary implications for the vertebrate lactate dehydrogenase gene family. [Proc Natl Acad Sci U S A. 1993]
Lactate dehydrogenase-B cDNA from the teleost Fundulus heteroclitus: evolutionary implications. [Mol Biol Evol. 1989]
A monophyletic origin of heart-predominant lactate dehydrogenase (LDH) isozymes of gnathostome vertebrates: evidence from the cDNA sequence of the spiny dogfish (Squalus acanthias) LDH-B. [Mol Mar Biol Biotechnol. 1998]
ReviewSome aspects of isozymes of lactate dehydrogenase, malate dehydrogenase and glucosephosphate isomerase in fish. [Comp Biochem Physiol B. 1989]
ReviewThe use of enzyme kinetics to predict differences in cellular metabolism, developmental rate, and swimming performance between LDH-B genotypes of the fish, fundulus heteroclitus. [Isozymes Curr Top Biol Med Res. 1983]

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Evolutionary relations among vertebrate muscle-type lactate dehydrogenases.

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