Molecular cloning of human liver sulfite oxidase. [Biochim Biophys Acta. 1995]

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1: Biochim Biophys Acta. 1995 Jun 9;1262(2-3):147-9.Links

Molecular cloning of human liver sulfite oxidase.

Garrett RM, Bellissimo DB, Rajagopalan KV.

Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

A 2.4 kilobase cDNA clone of human sulfite oxidase was isolated from a human liver cDNA library in lambda gt10. Comparison of three sulfite oxidase sequences to several plant and fungal nitrate reductase sequences reveals a single conserved cysteine with highly conserved flanking sequences. The conserved cysteine is postulated to be a ligand of molybdenum in sulfite oxidase and nitrate reductase.

PMID: 7599189 [PubMed - indexed for MEDLINE]

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ReviewA review of the clinical presentation and laboratory findings in two uncommon hereditary disorders of sulfur amino acid metabolism, beta-mercaptolactate cysteine disulfideuria and sulfite oxidase deficiency. [Clin Biochem. 1985]
ReviewPrenatal diagnosis of molybdenum cofactor deficiency and isolated sulfite oxidase deficiency. [Prenat Diagn. 2003]

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Molecular cloning of human liver sulfite oxidase.

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