Steady state transcript levels of the type II hexokinase and type 1 glucose transporter in human tumor cell lines

Y Shinohara; K Yamamoto; K Kogure; J Ichihara; H Terada

doi:10.1016/0304-3835(94)90142-2

Steady state transcript levels of the type II hexokinase and type 1 glucose transporter in human tumor cell lines

Cancer Lett. 1994 Jul 15;82(1):27-32. doi: 10.1016/0304-3835(94)90142-2.

Authors

Y Shinohara¹, K Yamamoto, K Kogure, J Ichihara, H Terada

Affiliation

¹ Faculty of Pharmaceutical Sciences, University of Tokushima, Japan.

PMID: 7518342
DOI: 10.1016/0304-3835(94)90142-2

Abstract

The steady state transcript levels of two hexokinase isozymes and type 1 glucose transporter in human tumor cell lines were analyzed. In HepG2 cells, both type II hexokinase and type 1 glucose transporter were highly expressed. However, in cell lines A431 and HeLa, in which the expression level of type 1 glucose transporter was lower than that in HepG2 cells, the amount of type II hexokinase transcript was almost negligible.

MeSH terms

Amino Acid Sequence
Base Sequence
HeLa Cells
Hexokinase / biosynthesis
Hexokinase / genetics*
Humans
Molecular Sequence Data
Monosaccharide Transport Proteins / biosynthesis
Monosaccharide Transport Proteins / genetics*
RNA / analysis
Recombinant Proteins / biosynthesis
Transcription, Genetic
Tumor Cells, Cultured

Substances

Monosaccharide Transport Proteins
Recombinant Proteins
RNA
Hexokinase

Associated data

GENBANK/D25411
GENBANK/D25412