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Molecular cloning of the human gastrin gene.
A genomic clone that contains the human gastrin gene was isolated from a human gene library. Restriction endonuclease mapping and DNA sequencing analysis revealed that this gene is about 0.7 kb long, and has an intron. The intron is located at a position that separates the coding region into the peptide region essential for biological activities of gastrin and the non-essential, N-terminal peptide region.
PMID: 6324077 [PubMed - indexed for MEDLINE]
PMCID: PMC326575
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