Persistent infection of primary human cell cultures with rubella variant carrying DNA Polymerase activity

Arch Virol. 1978;56(1-2):181-7. doi: 10.1007/BF01317294.

Abstract

Infection of primary human cells with a rubella variant carrying DNA polymerase activity resulted in persistent infection; infection with wild type virus caused death of the infected cells and a cytopathic effect.

MeSH terms

  • Culture Techniques
  • DNA-Directed DNA Polymerase / genetics
  • DNA-Directed DNA Polymerase / metabolism*
  • Genetic Variation
  • Humans
  • Rubella virus / enzymology
  • Rubella virus / genetics
  • Rubella virus / growth & development*
  • Transfection
  • Virus Replication

Substances

  • DNA-Directed DNA Polymerase