Abstract
Phosphatidylcholine vesicles stimulate the activity of the DNA polymerase-alpha from calf thymus. This effect is dependent upon the way of addition to the Mg ions, and the extent of the 3H-dTTP incorporation is closely related to the concentration of the vesicles. A role of phospholipids on the activity of the DNA-related enzymes is suggested.
MeSH terms
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Animals
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Cattle
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DNA Polymerase II / metabolism*
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DNA-Directed DNA Polymerase / metabolism*
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Magnesium / pharmacology
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Membranes, Artificial*
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Phosphatidylcholines / metabolism*
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Thymine Nucleotides / metabolism
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Thymus Gland / enzymology*
Substances
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Membranes, Artificial
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Phosphatidylcholines
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Thymine Nucleotides
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DNA Polymerase II
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DNA-Directed DNA Polymerase
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Magnesium