Silencing of ARHGAP21, a Rho GTPase activating protein (RhoGAP), reduces the growth of prostate cancer xenografts in NOD/SCID mice

Biochim Biophys Acta Mol Cell Res. 2023 Apr;1870(4):119439. doi: 10.1016/j.bbamcr.2023.119439. Epub 2023 Feb 9.
No abstract available

Keywords: ARHGAP21; PC3 cells; Prostate cancer; RhoGAP.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • GTPase-Activating Proteins* / metabolism
  • Heterografts
  • Humans
  • Male
  • Mice
  • Mice, Inbred NOD
  • Mice, SCID
  • Prostatic Neoplasms* / genetics

Substances

  • rho GTPase-activating protein
  • GTPase-Activating Proteins
  • ARHGAP21 protein, human