Abstract
We have localized the human gene for erythroid potentiating activity (EPA) to the X chromosome by analysis of its segregation pattern in mouse-human somatic cell hybrids. The EPA gene has been further localized to human chromosome region Xp11.1----Xp11.4 by in situ hybridization of a molecularly cloned EPA genomic fragment to metaphase chromosomes.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Chromosome Mapping*
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DNA / genetics
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Genetic Markers
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Glycoproteins / genetics
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Humans
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Hybrid Cells
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Karyotyping
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Lymphokines / genetics*
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Mice
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Nucleic Acid Hybridization
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Tissue Inhibitor of Metalloproteinases
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X Chromosome*
Substances
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Genetic Markers
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Glycoproteins
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Lymphokines
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Tissue Inhibitor of Metalloproteinases
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DNA