Localization of the gene encoding human erythroid-potentiating activity to chromosome region Xp11.1----Xp11.4

Am J Hum Genet. 1986 Jun;38(6):819-26.

Abstract

We have localized the human gene for erythroid potentiating activity (EPA) to the X chromosome by analysis of its segregation pattern in mouse-human somatic cell hybrids. The EPA gene has been further localized to human chromosome region Xp11.1----Xp11.4 by in situ hybridization of a molecularly cloned EPA genomic fragment to metaphase chromosomes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Mapping*
  • DNA / genetics
  • Genetic Markers
  • Glycoproteins / genetics
  • Humans
  • Hybrid Cells
  • Karyotyping
  • Lymphokines / genetics*
  • Mice
  • Nucleic Acid Hybridization
  • Tissue Inhibitor of Metalloproteinases
  • X Chromosome*

Substances

  • Genetic Markers
  • Glycoproteins
  • Lymphokines
  • Tissue Inhibitor of Metalloproteinases
  • DNA