Some aspects of DNA polymerase functioning

A A Krayevsky; M K Kukhanova; R Sh Beabealashvilli; Z G Chidgeavadze

Some aspects of DNA polymerase functioning

Nucleic Acids Symp Ser. 1987:(18):121-4.

Authors

A A Krayevsky¹, M K Kukhanova, R Sh Beabealashvilli, Z G Chidgeavadze

Affiliation

¹ Institute of Molecular Biology, USSR Academy of Sciences, Moscow.

PMID: 3320974

Abstract

The group of DNA polymerases was studied using some new nucleoside 5'-triphosphate analogs with termination substrate properties. Among DNA polymerases tested the least specific appeared reverse transcriptases of retroviruses and the most specific were DNA polymerases alpha type from high eucaryotes including mammalians.

Publication types

Comparative Study

MeSH terms

Animals
Avian Myeloblastosis Virus / enzymology
Cattle
DNA / biosynthesis
DNA-Directed DNA Polymerase / metabolism*
Deoxyribonucleotides / chemical synthesis*
Escherichia coli / enzymology
Liver / enzymology
Rats
Substrate Specificity
T-Phages / enzymology
Thymus Gland / enzymology

Substances

Deoxyribonucleotides
DNA
DNA-Directed DNA Polymerase