The structural gene for the mitochondrial aldehyde dehydrogenase maps to human chromosome 12

Hum Genet. 1986 Aug;73(4):365-7. doi: 10.1007/BF00279102.

Abstract

A cloned 850 bp cDNA fragment corresponding to the 3'-coding part of human ALDHI-mRNA was used as a probe for the chromosomal assignment of the ALDHI gene. Southern blot analysis of human-rodent somatic cell hybrids indicates that the human ALDHI gene resides on chromosome 12.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Dehydrogenase / genetics*
  • Animals
  • Chromosome Mapping*
  • Chromosomes, Human, 6-12 and X*
  • DNA Restriction Enzymes
  • Genes*
  • Humans
  • Hybrid Cells
  • Isoenzymes / genetics
  • Mitochondria, Liver / enzymology*

Substances

  • Isoenzymes
  • Aldehyde Dehydrogenase
  • DNA Restriction Enzymes