Disruption of Tdrd5 decouples the stepwise processing of long precursor transcripts during pachytene PIWI-interacting RNA biogenesis

Biol Reprod. 2018 Oct 1;99(4):684-685. doi: 10.1093/biolre/ioy110.

Authors

Yu H Sun¹, Feng Jiang¹, Xin Zhiguo Li¹

Affiliation

¹ Center for RNA Biology: From Genome to Therapeutics, Department of Biochemistry and Biophysics, Department of Urology, University of Rochester Medical Center, Rochester, New York, USA.

PMID: 29733347
DOI: 10.1093/biolre/ioy110

No abstract available

MeSH terms

Animals
Male
Mice
Mice, Knockout
Models, Biological
Pachytene Stage / genetics
Proteins / genetics*
Proteins / metabolism*
RNA Precursors / genetics
RNA Precursors / metabolism
RNA Processing, Post-Transcriptional
RNA, Small Interfering / genetics*
RNA, Small Interfering / metabolism*
Spermatids / cytology
Spermatids / metabolism
Spermatocytes / cytology
Spermatocytes / metabolism
Spermatogenesis / genetics
Testis / metabolism
Testis / pathology

Substances

Proteins
RNA Precursors
RNA, Small Interfering
Tdrd5 protein, mouse