Epithelioid sarcoma of the plantar fascia mimicking Morbus Ledderhose - A severe pitfall for clinical and histopathological misinterpretation

Foot Ankle Surg. 2017 Dec;23(4):e25-e30. doi: 10.1016/j.fas.2017.03.013. Epub 2017 Apr 5.

Abstract

Plantar fibromatosis, also known as Morbus Ledderhose, is a well known and frequently encountered disorder of the planta pedis. When conservative treatment fails, surgical therapy with complete resection is the therapeutical procedure of choice. Soft tissue sarcoma is a heterogeneous and rare malignant disease of the musculoskeletal system with over 50 histopathological subtypes which can potentially arise in any localization but is most commonly found at the extremities. Here, we report the case of an epithelioid sarcoma of the sole of the foot which was initially and repeatedly clinically and histopathologically misinterpreted as plantar fibromatosis, receiving insufficient resection and subsequently ending in amputation of the lower leg.

Keywords: Epithelioid sarcoma; Foot tumor; Morbus Ledderhose; Musculoskeletal tumor; Plantar fibromatosis; Soft tissue sarcoma; Unplanned resection.

Publication types

  • Case Reports

MeSH terms

  • Amputation, Surgical
  • Delayed Diagnosis
  • Diagnosis, Differential
  • Fascia / diagnostic imaging
  • Fascia / pathology*
  • Female
  • Fibroma / diagnosis
  • Fibroma / diagnostic imaging
  • Fibroma / pathology*
  • Fibroma / surgery
  • Foot / diagnostic imaging
  • Foot / pathology
  • Foot / physiology*
  • Foot / surgery
  • Foot Diseases / diagnosis
  • Foot Diseases / diagnostic imaging
  • Foot Diseases / pathology*
  • Foot Diseases / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Sarcoma / diagnosis
  • Sarcoma / diagnostic imaging
  • Sarcoma / pathology*
  • Sarcoma / surgery
  • Soft Tissue Neoplasms / diagnosis
  • Soft Tissue Neoplasms / diagnostic imaging
  • Soft Tissue Neoplasms / pathology*
  • Soft Tissue Neoplasms / surgery